Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14878824 | 0.90 | ALDH1A1 (0.35) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL13523902 | 0.88 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL10029404 | 0.87 | ALDH1A1 (0.49) | ALDH1A1TSHRHSD17B10TDP1PDE4D | |
| SCHEMBL13015080 | 0.86 | PDE4D (0.36) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL12981685 | 0.86 | PPARG (0.42) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL25620254 | 0.82 | PDE4D (0.42) | CYP3A4TSHRPDE4DHTR2A | |
| SCHEMBL13070210 | 0.79 | TOP1 (0.39) | HTR2ATOP1 | |
| SCHEMBL1597428 | 0.79 | ALDH1A1 (0.59) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL1299603 | 0.78 | ALDH1A1 (0.44) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL14878835 | 0.77 | ERAP2 (0.30) | ERAP2LNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049599-B1 | BASIC BISAZO COMPOUNDS | ARCHROMA IP GMBH (CH) | 2017-02-22 | — | — | EP | disclosed |
| US-8921564-B2 | Basic bisazo compounds | CLARIANT FINANCE (BVI) LTD. (VG) | 2014-12-30 | — | — | US | disclosed |
| US-8921564-B2 | Basic bisazo compounds | CLARIANT FINANCE (BVI) LTD. (VG) | 2014-12-30 | — | — | US | disclosed |
| US-20100000033-A1 | Basic Bisazo Compounds | CLARIANT FINANCE (BVI) LIMITED (VG) | 2010-01-07 | — | — | US | disclosed |
| US-20100000033-A1 | Basic Bisazo Compounds | CLARIANT FINANCE (BVI) LIMITED (VG) | 2010-01-07 | — | — | US | disclosed |
| EP-2078737-A1 | Basic monoazo compounds | Clariant International Ltd. (CH) | 2009-07-15 | — | — | EP | disclosed |
| WO-2008012322-A1 | BASIC BISAZO COMPOUNDS | CLARIANT INTERNATIONAL LTD (CH) | 2008-01-31 | — | — | WO | disclosed |