Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 10/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13523930 | 0.80 | ESR1 (0.52) | TDP1NPC1MAPTRAB9AESR1 | |
| SCHEMBL746951 | 0.80 | ESR1 (0.58) | TDP1NPC1MAPTRAB9AESR1 | |
| SCHEMBL21504867 | 0.77 | MAPT (0.46) | TDP1NPC1MAPTRAB9AESR1 | |
| SCHEMBL13523925 | 0.77 | TDP1 (0.44) | TDP1NPC1MAPTRAB9AESR1 | |
| SCHEMBL13523933 | 0.77 | ESR1 (0.55) | NPC1MAPTRAB9AESR1ESR2 | |
| SCHEMBL13523932 | 0.76 | ESR1 (0.48) | NPC1MAPTRAB9AESR1ESR2 | |
| SCHEMBL13523934 | 0.74 | CNR2 (0.49) | NPC1MAPTRAB9AESR1ESR2 | |
| SCHEMBL13523936 | 0.74 | NPC1 (0.40) | TDP1NPC1MAPTRAB9AESR1 | |
| SCHEMBL13523939 | 0.74 | TDP1 (0.39) | TDP1NPC1MAPTRAB9AESR1 | |
| SCHEMBL8771461 | 0.71 | CYP3A4 (0.48) | TDP1NPC1MAPTRAB9AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049599-B1 | BASIC BISAZO COMPOUNDS | ARCHROMA IP GMBH (CH) | 2017-02-22 | — | — | EP | disclosed |
| US-8921564-B2 | Basic bisazo compounds | CLARIANT FINANCE (BVI) LTD. (VG) | 2014-12-30 | — | — | US | disclosed |
| US-8921564-B2 | Basic bisazo compounds | CLARIANT FINANCE (BVI) LTD. (VG) | 2014-12-30 | — | — | US | disclosed |
| US-20100000033-A1 | Basic Bisazo Compounds | CLARIANT FINANCE (BVI) LIMITED (VG) | 2010-01-07 | — | — | US | disclosed |
| US-20100000033-A1 | Basic Bisazo Compounds | CLARIANT FINANCE (BVI) LIMITED (VG) | 2010-01-07 | — | — | US | disclosed |
| WO-2008012322-A1 | BASIC BISAZO COMPOUNDS | CLARIANT INTERNATIONAL LTD (CH) | 2008-01-31 | — | — | WO | disclosed |