Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | BLM | P54132 | 2/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 3/20 | 0.52 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PLEC | Q15149 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16295013 | 0.99 | MEN1 (0.98) | MEN1KMT2ABLMTHRBRECQL | |
| SCHEMBL14013408 | 0.88 | MEN1 (0.79) | MEN1KMT2ABLMTHRBRECQL | |
| SCHEMBL14046504 | 0.87 | MEN1 (0.77) | MEN1KMT2ABLMTHRBRECQL | |
| SCHEMBL13524213 | 0.86 | MEN1 (0.75) | MEN1KMT2ABLMTHRBRECQL | |
| SCHEMBL13428244 | 0.86 | MEN1 (0.75) | MEN1KMT2ABLMTHRBRECQL | |
| SCHEMBL12192021 | 0.85 | MEN1 (0.74) | MEN1KMT2ABLMTHRBRECQL | |
| SCHEMBL574910 | 0.85 | MEN1 (0.74) | MEN1KMT2ABLMTHRBRECQL | |
| SCHEMBL21648601 | 0.85 | MEN1 (0.73) | MEN1KMT2ABLMTHRBRECQL | |
| Bromide SCHEMBL30740862 | 0.84 | MEN1 (0.72) | MEN1KMT2ABLMTHRBRECQL | |
| SCHEMBL17124185 | 0.84 | MEN1 (0.72) | MEN1KMT2ABLMTHRBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701841-B2 | Cell permeable, fluorescent dye | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2017-07-11 | — | — | US | disclosed |
| EP-2748173-B1 | CELL PERMEABLE, FLUORESCENT DYE | ECOLE POLYTECH (CH) | 2016-11-23 | — | — | EP | disclosed |
| US-9346957-B2 | Cell permeable, fluorescent dye | ÉCOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL) (CH) | 2016-05-24 | — | — | US | disclosed |
| US-20140349282-A1 | Cell Permeable, Fluorescent Dye | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2014-11-27 | — | — | US | disclosed |
| WO-2013029650-A1 | CELL PERMEABLE, FLUORESCENT DYE | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2013-03-07 | — | — | WO | disclosed |
| US-20100008857-A1 | NOVEL HEXATRIENE-BETA-CARBONYL COMPOUND | OSAKA UNIVERSITY (JP) | 2010-01-14 | — | — | US | disclosed |
| US-20090072197-A1 | FLUORESCENT POLYMERIC MATERIALS CONTAINING LIPID SOLUBLE RHODAMINE DYES | APPLIED BIOSYSTEMS INC. (US) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100008857-A1 | NOVEL HEXATRIENE-BETA-CARBONYL COMPOUND | CBR1, CBR3, DCXR | MEN1 4487/4885KMT2A 2375/4885BLM 4479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.