SCHEMBL13428244

SCHEMBL13428244

Cc1ccccc1-c1c2ccc(=[N+](C)C)cc-2oc2cc(N(C)C)ccc12

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.75
▸ BLM P54132 2/20 0.75
▸ KMT2A Q03164 2/20 0.75
▸ THRB P10828 1/20 0.75
▸ RECQL P46063 1/20 0.75
▸ TDP1 Q9NUW8 1/20 0.75
▸ P2RY6 Q15077 1/20 0.51
▸ USP2 O75604 2/20 0.47
▸ APAF1 O14727 1/20 0.47
▸ RAB9A P51151 1/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ ABCB1 P08183 2/20 0.44
▸ CA12 O43570 3/20 0.41
▸ CA1 P00915 3/20 0.41
▸ CA2 P00918 3/20 0.41
▸ CA9 Q16790 3/20 0.41
▸ POLB P06746 1/20 0.40
▸ PPARG P37231 1/20 0.40
▸ RXFP1 Q9HBX9 1/20 0.40
▸ NCOR2 Q9Y618 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21648601 0.87 MEN1 (0.73) MEN1BLMKMT2ATHRBRECQL
SCHEMBL13525202 0.86 MEN1 (1.00) MEN1BLMKMT2ATHRBRECQL
SCHEMBL26213880 0.85 MEN1 (0.71) MEN1BLMKMT2ATHRBRECQL
Hydrochloric Acid SCHEMBL16295013 0.85 MEN1 (0.98) MEN1BLMKMT2ATHRBRECQL
SCHEMBL12598704 0.84 MEN1 (0.69) MEN1BLMKMT2ATHRBRECQL
SCHEMBL16350945 0.84 MEN1 (0.69) MEN1BLMKMT2ATHRBRECQL
Tetramethylrhodamine SCHEMBL2054818 0.84 MEN1 (0.71) MEN1BLMKMT2ATHRBRECQL
SCHEMBL25340481 0.84 MEN1 (0.54) MEN1BLMKMT2ATHRBRECQL
SCHEMBL25340474 0.84 MEN1 (0.54) MEN1BLMKMT2ATHRBRECQL
SCHEMBL12418867 0.83 MEN1 (0.67) MEN1BLMKMT2ATHRBRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230321226-A1 SYNTHETIC ARCHAEAL DIETHER LIPIDS APHP (ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS) (FR) 2023-10-12 — — US disclosed
US-11560365-B2 Non-fluorescent rhodamines THE UNIVERSITY OF TOKYO (JP) 2023-01-24 — — US disclosed
US-20210087160-A1 NOVEL NON-FLUORESCENT RHODAMINES THE UNIVERSITY OF TOKYO (JP) 2021-03-25 — — US disclosed
US-9939454-B2 Fluorogenic pH sensitive dyes and their method of use Life Technologies Corporation (US) 2018-04-10 — — US disclosed
US-9910051-B2 Fluorogenic pH sensitive dyes and their method of use Life Technologies Corporation (US) 2018-03-06 — — US disclosed
US-20170145214-A1 FLUOROGENIC PH-SENSITIVE DYES AND THEIR METHODS OF USE (II) Life Technologies Corporation 2017-05-25 — — US disclosed
US-9599622-B2 Fluorogenic pH-sensitive dyes and their methods of use (II) Life Technologies Corporation (US) 2017-03-21 — — US disclosed
US-20160139158-A1 FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE Life Technologies Corporation 2016-05-19 — — US disclosed
US-20150241438-A1 Fluorogenic pH-Sensitive Dyes and Their Methods of Use Life Technologies Corporation 2015-08-27 — — US disclosed
US-20150218379-A1 Fluorogenic pH-Sensitive Dyes and Their Methods of Use (II) Life Technologies Corporation 2015-08-06 — — US disclosed
US-20150037834-A1 FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE Life Technologies Corporation 2015-02-05 — — US disclosed
US-8766238-B2 Polymeric anions/cations MERCK PATENT GMBH (DE) 2014-07-01 — — US disclosed
US-20130102021-A1 FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE Life Technologies Corporation (US) 2013-04-25 — — US disclosed
US-20100059740-A1 POLYMERIC ANIONS/CATIONS MERCK PATENT GMBH (DE) 2010-03-11 — — US disclosed
US-20100059740-A1 POLYMERIC ANIONS/CATIONS MERCK PATENT GMBH (DE) 2010-03-11 — — US disclosed
US-20080274907-A1 FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE INVITROGEN CORPORATION (US) 2008-11-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230321226-A1 SYNTHETIC ARCHAEAL DIETHER LIPIDS DDOST, ABHD16A, GMDS MEN1 2422/4885BLM 931/4885KMT2A 3351/4885
US-20210087160-A1 NOVEL NON-FLUORESCENT RHODAMINES QTRT1, QTRT2, NONO MEN1 2300/4885BLM 1503/4885KMT2A 2558/4885
US-20080274907-A1 FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE SLC11A2, MAN2B1, CD47 MEN1 1603/4885BLM 3585/4885KMT2A 4285/4885
US-20150241438-A1 Fluorogenic pH-Sensitive Dyes and Their Methods of Use ALPG, XDH, HEXD MEN1 1191/4885BLM 1463/4885KMT2A 3268/4885
US-11560365-B2 Non-fluorescent rhodamines QTRT1, QTRT2, NONO MEN1 2015/4885BLM 1478/4885KMT2A 2755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback