Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PLK4 | O00444 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28163000 | 1.00 | HSD17B10 (0.64) | HSD17B10NR4A1NR4A2NR4A3KDM4E | |
| SCHEMBL157601 | 0.91 | KDM4E (0.55) | HSD17B10KDM4EALDH1A1GAAPARP1 | |
| SCHEMBL14837758 | 0.89 | KDM4E (0.53) | HSD17B10KDM4EALDH1A1GAAPARP1 | |
| Benzene SCHEMBL28110156 | 0.89 | HSD17B10 (0.78) | HSD17B10NR4A1NR4A2NR4A3KDM4E | |
| SCHEMBL68291 | 0.89 | HSD17B10 (0.78) | HSD17B10NR4A1NR4A2NR4A3KDM4E | |
| SCHEMBL29404347 | 0.89 | HSD17B10 (0.78) | HSD17B10NR4A1NR4A2NR4A3KDM4E | |
| SCHEMBL7624693 | 0.89 | HSD17B10 (0.78) | HSD17B10NR4A1NR4A2NR4A3KDM4E | |
| Charcoal, Activated SCHEMBL5746941 | 0.87 | HSD17B10 (0.75) | HSD17B10NR4A1NR4A2NR4A3KDM4E | |
| Hydrochloric Acid SCHEMBL10337055 | 0.87 | HSD17B10 (0.75) | HSD17B10NR4A1NR4A2NR4A3KDM4E | |
| Lithium SCHEMBL7732118 | 0.87 | HSD17B10 (0.75) | HSD17B10NR4A1NR4A2NR4A3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110277948-A1 | METHOD OF MONITORING AND INHIBITING SCALE DEPOSITION IN PULP MILL EVAPORATORS AND CONCENTRATORS | NALCO COMPANY | 2011-11-17 | — | — | US | claimed |
| EP-2142699-A1 | METHOD OF MONITORING AND INHIBITING SCALE DEPOSITION IN PULP MILL EVAPORATORS AND CONCENTRATORS | Nalco Company (US) | 2010-01-13 | — | — | EP | claimed |
| WO-2008141121-A1 | METHOD OF MONITORING AND INHIBITING SCALE DEPOSITION IN PULP MILL EVAPORATORS AND CONCENTRATORS | NALCO COMPANY (US) | 2008-11-20 | — | — | WO | claimed |
| US-20080277083-A1 | METHOD OF MONITORING AND INHIBITING SCALE DEPOSITION IN PULP MILL EVAPORATORS AND CONCENTRATORS | ECOLAB USA INC. | 2008-11-13 | — | — | US | claimed |
| CN-117603148-A | Pharmacokinetic enhancement of difunctional chelates and uses thereof | 探针技术开发及商业化中心 | 2024-02-27 | — | — | CN | disclosed |
| CN-111263747-B | Pharmacokinetic enhancement of difunctional chelates and uses thereof | 探针技术开发及商业化中心 | 2023-10-27 | — | — | CN | disclosed |
| US-20220411582-A1 | POLYALKYLENEIMINE-BASED POLYMERS CONTAINING POLYETHER CHAINS | BASF SE (DE) | 2022-12-29 | — | — | US | disclosed |
| US-20220403106-A1 | POLYALKYLENEIMINE-BASED POLYMER CONTAINING POLYETHER CHAINS | BASF SE (DE) | 2022-12-22 | — | — | US | disclosed |
| US-8450726-B2 | Articles containing coatings of amic acid salts | EASTMAN KODAK COMPANY (US) | 2013-05-28 | — | — | US | disclosed |
| US-8431433-B2 | Methods of providing semiconductor layers from amic acid salts | EASTMAN KODAK COMPANY (US) | 2013-04-30 | — | — | US | disclosed |
| EP-2576501-A1 | AROMATIC AMIC ACID SALTS AND COMPOSITIONS | Eastman Kodak Company (US) | 2013-04-10 | — | — | EP | disclosed |
| US-8404892-B2 | Aromatic amic acid salts and compositions | EASTMAN KODAK COMPANY (US) | 2013-03-26 | — | — | US | disclosed |
| US-6395749-B1 | Carboxamide compounds, methods, and compositions for inhibiting PARP activity | GUILFORD PHARMACEUTICALS INC. | 2002-05-28 | — | — | US | disclosed |
| WO-2002032856-A2 | INSECTICIDAL 1,8-NAPHTHALENEDICARBOXAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-04-25 | — | — | WO | disclosed |
| US-20020019417-A1 | Methods, compounds and compositions for treating gout | EISAI INC. | 2002-02-14 | — | — | US | disclosed |
| WO-2001091796-A2 | METHODS, COMPOUNDS AND COMPOSITIONS FOR TREATING GOUT | GUILFORD PHARMACEUTICALS INC. (US) | 2001-12-06 | — | — | WO | disclosed |
| EP-1077944-A1 | CARBOXAMIDE COMPOUNDS, COMPOSITIONS, AND METHODS FOR INHIBITING PARP ACTIVITY | GUILFORD PHARMACEUTICALS INC. (US) | 2001-02-28 | — | — | EP | disclosed |
| EP-1012153-A1 | PARP INHIBITORS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS OF USING SAME | GUILFORD PHARMACEUTICALS INC. (US) | 2000-06-28 | — | — | EP | disclosed |
| WO-1999059973-A1 | CARBOXAMIDE COMPOUNDS, COMPOSITIONS, AND METHODS FOR INHIBITING PARP ACTIVITY | GUILFORD PHARMACEUTICALS INC. (US) | 1999-11-25 | — | — | WO | disclosed |
| WO-1999011649-A2 | PARP INHIBITORS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS OF USING SAME | GUILFORD PHARMACEUTICALS INC. (US) | 1999-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019417-A1 | Methods, compounds and compositions for treating gout | PARP2, PARP1, PARP3 | HSD17B10 735/4885NR4A1 3900/4885NR4A2 4045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.