SCHEMBL28163000

SCHEMBL28163000

NC(=O)c1cccc2cccc(C(=O)O)c12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.64
NR4A1 P22736 1/20 0.50
NR4A2 P43354 1/20 0.50
NR4A3 Q92570 1/20 0.50
KDM4E B2RXH2 3/20 0.48
ALDH1A1 P00352 3/20 0.48
GAA P10253 1/20 0.48
PARP1 P09874 3/20 0.47
MAPT P10636 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
PDPK1 O15530 1/20 0.47
ALOX15 P16050 1/20 0.46
CYP1A2 P05177 1/20 0.46
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
PLK4 O00444 1/20 0.44
CHEK1 O14757 1/20 0.44
AURKA O14965 1/20 0.44
DAPK3 O43293 1/20 0.44
MAP4K4 O95819 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1353024 1.00 HSD17B10 (0.64) HSD17B10NR4A1NR4A2NR4A3KDM4E
SCHEMBL157601 0.91 KDM4E (0.55) HSD17B10KDM4EALDH1A1GAAPARP1
SCHEMBL14837758 0.89 KDM4E (0.53) HSD17B10KDM4EALDH1A1GAAPARP1
Benzene SCHEMBL28110156 0.89 HSD17B10 (0.78) HSD17B10NR4A1NR4A2NR4A3KDM4E
SCHEMBL68291 0.89 HSD17B10 (0.78) HSD17B10NR4A1NR4A2NR4A3KDM4E
SCHEMBL29404347 0.89 HSD17B10 (0.78) HSD17B10NR4A1NR4A2NR4A3KDM4E
SCHEMBL7624693 0.89 HSD17B10 (0.78) HSD17B10NR4A1NR4A2NR4A3KDM4E
Charcoal, Activated SCHEMBL5746941 0.87 HSD17B10 (0.75) HSD17B10NR4A1NR4A2NR4A3KDM4E
Hydrochloric Acid SCHEMBL10337055 0.87 HSD17B10 (0.75) HSD17B10NR4A1NR4A2NR4A3KDM4E
Lithium SCHEMBL7732118 0.87 HSD17B10 (0.75) HSD17B10NR4A1NR4A2NR4A3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111918712-A Functionalized polyimides and membranes for gas separation 赢创(上海)投资管理有限公司 2020-11-10 CN claimed
CN-111918712-A Functionalized polyimides and membranes for gas separation 赢创(上海)投资管理有限公司 2020-11-10 CN disclosed
CN-107043351-A A kind of synthesis of Ultraluminescence molecular probe and its detection to nitrite anions 兰州大学 2017-08-15 CN disclosed