Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13530350 | 0.82 | PPARD (0.45) | PPARDTSHRTP53TDP1 | |
| SCHEMBL4882046 | 0.81 | PPARD (0.56) | PPARDTSHRTP53TDP1 | |
| SCHEMBL4164665 | 0.81 | PPARD (0.56) | PPARDTSHRTP53TDP1 | |
| SCHEMBL4881306 | 0.81 | PPARD (0.56) | PPARDTSHRTP53TDP1 | |
| SCHEMBL9000185 | 0.79 | TSHR (0.46) | PPARDTSHRAOX1TP53TDP1 | |
| SCHEMBL23786286 | 0.77 | PPARD (0.52) | PPARDTSHRTP53TDP1 | |
| SCHEMBL19352052 | 0.77 | PPARD (0.52) | PPARDTSHRTP53TDP1 | |
| SCHEMBL23430674 | 0.77 | PPARD (0.52) | PPARDTSHRTP53TDP1 | |
| SCHEMBL3220479 | 0.75 | PPARD (0.50) | PPARDTSHRTP53TDP1 | |
| SCHEMBL2382808 | 0.74 | PPARD (0.54) | PPARDTSHRAOX1TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100022467-A1 | ANTI-CANCER PHOSPHONATE ANALOGS | BOOJAMRA CONSTANTINE G | 2010-01-28 | — | — | US | disclosed |
| US-20100022467-A1 | ANTI-CANCER PHOSPHONATE ANALOGS | BOOJAMRA CONSTANTINE G | 2010-01-28 | — | — | US | disclosed |
| US-7452901-B2 | Anti-cancer phosphonate analogs | GILEAD SCIENCES, INC. (US) | 2008-11-18 | — | — | US | disclosed |
| US-7452901-B2 | Anti-cancer phosphonate analogs | GILEAD SCIENCES, INC. (US) | 2008-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022467-A1 | ANTI-CANCER PHOSPHONATE ANALOGS | PIK3CA, PHOSPHO1, PTEN | PPARD 1752/4885TSHR 4311/4885AOX1 4211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.