Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499680 | 0.81 | TSHR (0.60) | TSHRPPARDTP53TDP1MEN1 | |
| SCHEMBL9858061 | 0.81 | TSHR (0.44) | TSHRPPARDTP53TDP1MEN1 | |
| SCHEMBL13530352 | 0.79 | PPARD (0.47) | TSHRPPARDTP53TDP1AOX1 | |
| SCHEMBL7940743 | 0.79 | TSHR (0.57) | TSHRPPARDTP53TDP1MEN1 | |
| SCHEMBL9304075 | 0.75 | TSHR (0.52) | TSHRPPARDTP53TDP1MEN1 | |
| SCHEMBL1378158 | 0.72 | TSHR (0.55) | TSHRPPARDTP53TDP1AOX1 | |
| SCHEMBL28994311 | 0.71 | TSHR (0.48) | TSHRPPARDTP53TDP1MEN1 | |
| SCHEMBL19352052 | 0.71 | PPARD (0.52) | TSHRPPARDTP53TDP1MEN1 | |
| SCHEMBL441144 | 0.70 | — | — | |
| SCHEMBL9648810 | 0.70 | TSHR (0.65) | TSHRPPARDTP53TDP1AOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730408-A1 | TRIAZOLE PHOSPHONATE PESTICIDES | AgrEvo UK Limited (GB) | 1996-09-11 | — | — | EP | disclosed |
| WO-1995014385-A1 | TRIAZOLE PHOSPHONATE PESTICIDES | AGREVO UK LIMITED (GB) | 1995-06-01 | — | — | WO | disclosed |