Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.76 |
| ▸ | THRB | P10828 | 1/20 | 0.71 |
| ▸ | CASP3 | P42574 | 2/20 | 0.66 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.66 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.66 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.62 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.60 |
| ▸ | CPT2 | P23786 | 1/20 | 0.59 |
| ▸ | CPT1A | P50416 | 1/20 | 0.59 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449594 | 0.95 | MEN1 (0.84) | MEN1KMT2ATHRBCASP3SENP8 | |
| SCHEMBL2828714 | 0.89 | MEN1 (0.74) | MEN1KMT2ATHRBCASP3SENP8 | |
| SCHEMBL13532188 | 0.88 | MEN1 (0.83) | MEN1KMT2ATHRBCASP3SENP8 | |
| SCHEMBL7366821 | 0.87 | AKR1C3 (0.67) | MEN1KMT2ATHRBMAPTPFKFB3 | |
| SCHEMBL14485525 | 0.87 | MAPT (0.82) | MEN1KMT2ATHRBMAPTPKM | |
| SCHEMBL3502755 | 0.86 | MEN1 (1.00) | MEN1KMT2ATHRBCASP3SENP8 | |
| SCHEMBL2825155 | 0.86 | CPT1A (0.71) | MEN1KMT2ATHRBCASP3SENP8 | |
| SCHEMBL27179830 | 0.86 | MEN1 (0.69) | MEN1KMT2ATHRBCASP3SENP8 | |
| SCHEMBL13532190 | 0.85 | MEN1 (0.71) | MEN1KMT2ATHRBCASP3SENP8 | |
| SCHEMBL2825370 | 0.85 | KMT2A (0.79) | MEN1KMT2ATHRBCASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016310-A1 | METHODS OF USING ARYL SULFONYL COMPOUNDS EFFECTIVE AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-01-21 | — | — | US | disclosed |
| US-20100016310-A1 | METHODS OF USING ARYL SULFONYL COMPOUNDS EFFECTIVE AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016310-A1 | METHODS OF USING ARYL SULFONYL COMPOUNDS EFFECTIVE AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | EPHX1, EPHX2, NCEH1 | MEN1 4563/4885KMT2A 2861/4885THRB 2507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.