Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.84 |
| ▸ | THRB | P10828 | 1/20 | 0.71 |
| ▸ | CASP3 | P42574 | 2/20 | 0.66 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.66 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.66 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.62 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13532166 | 0.95 | MEN1 (0.76) | MEN1KMT2ATHRBCASP3SENP8 | |
| SCHEMBL3502755 | 0.91 | MEN1 (1.00) | MEN1KMT2ATHRBCASP3SENP8 | |
| SCHEMBL27179830 | 0.91 | MEN1 (0.69) | MEN1KMT2ATHRBCASP3SENP8 | |
| SCHEMBL7366821 | 0.90 | AKR1C3 (0.67) | MEN1KMT2ATHRBMAPTSMN1; SMN2 | |
| SCHEMBL7449794 | 0.89 | MEN1 (0.67) | MEN1KMT2ATHRBCASP3SENP8 | |
| SCHEMBL13532197 | 0.88 | MEN1 (0.84) | MEN1KMT2ATHRBCASP3SENP8 | |
| SCHEMBL7444940 | 0.87 | MEN1 (0.65) | MEN1KMT2ATHRBLMNAMAPT | |
| SCHEMBL30926962 | 0.87 | MEN1 (0.66) | MEN1KMT2ATHRBLMNAMAPT | |
| SCHEMBL27181037 | 0.87 | MEN1 (0.66) | MEN1KMT2ATHRBLMNAMAPT | |
| SCHEMBL30927046 | 0.85 | MEN1 (0.66) | MEN1KMT2ALMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001098274-A2 | SULPHONAMIDE DERIVATIVES | CELLTECH CHIROSCIENCE LIMITED (GB) | 2001-12-27 | — | — | WO | claimed |
| WO-2001098274-A2 | SULPHONAMIDE DERIVATIVES | CELLTECH CHIROSCIENCE LIMITED (GB) | 2001-12-27 | — | — | WO | disclosed |