⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1696759 | 0.96 | FKBP5 (0.36) | — | |
| SCHEMBL574926 | 0.92 | — | — | |
| SCHEMBL1696783 | 0.85 | CRBN (0.42) | — | |
| SCHEMBL8262750 | 0.84 | — | — | |
| SCHEMBL1696738 | 0.74 | — | — | |
| SCHEMBL2637407 | 0.74 | FKBP5 (0.43) | — | |
| SCHEMBL13534173 | 0.72 | — | — | |
| SCHEMBL762774 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL8003961 | 0.67 | — | — | |
| SCHEMBL8736493 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021237223-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2021-11-25 | — | — | WO | disclosed |
| US-7649015-B2 | Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| US-20070010489-A1 | Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds | GILEAD SCIENCES, INC. | 2007-01-11 | — | — | US | disclosed |