Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13534619 | 0.93 | PDK2 (0.44) | PDK2TGFBR1MEN1KMT2ACYP1A2 | |
| SCHEMBL12325191 | 0.89 | PDK2 (0.45) | PDK2TGFBR1MEN1TP53PKM | |
| SCHEMBL17149214 | 0.85 | PDK2 (0.38) | PDK2 | |
| SCHEMBL6241818 | 0.82 | PDK2 (0.57) | PDK2KMT2ACYP1A2CYP2D6CYP19A1 | |
| SCHEMBL13658652 | 0.82 | ELANE (0.36) | PDK2MEN1KMT2ACYP2C19 | |
| SCHEMBL20023693 | 0.81 | PDK2 (0.44) | PDK2TGFBR1MEN1TP53PKM | |
| SCHEMBL18052350 | 0.81 | PDK2 (0.38) | PDK2CYP2C19 | |
| SCHEMBL13622053 | 0.81 | PDK2 (0.38) | PDK2CYP2C19 | |
| SCHEMBL14224561 | 0.80 | NPC1 (0.40) | PDK2MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL14207075 | 0.80 | PDK2 (0.35) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7652136-B2 | Diarylaminofluorene-based organometallic phosphors and organic light-emitting devices made with such compounds | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2010-01-26 | — | — | US | disclosed |
| US-20080091021-A1 | Diarylaminofluorene-based organometallic phosphors and organic light-emitting devices made with such compounds | HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY, THE (CN) | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080091021-A1 | Diarylaminofluorene-based organometallic phosphors and organic light-emitting devices made with such compounds | ORC3, MCM3, TEC | PDK2 2704/4885TGFBR1 2040/4885MEN1 580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.