Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13534588 | 0.91 | MAPK14 (0.35) | NPC1RAB9AKDM4EMAPTALDH1A1 | |
| SCHEMBL13534589 | 0.80 | PDK2 (0.43) | NPC1RAB9AKDM4ECYP1A2CYP2C19 | |
| SCHEMBL17149214 | 0.79 | PDK2 (0.38) | ALDH1A1PDK2 | |
| SCHEMBL13372342 | 0.77 | MAPT (0.38) | NPC1RAB9AKDM4EMAPTALDH1A1 | |
| SCHEMBL13357121 | 0.77 | MAPT (0.38) | NPC1RAB9AKDM4EMAPTALDH1A1 | |
| SCHEMBL13658652 | 0.76 | ELANE (0.36) | MAPTALDH1A1HPGDMAPK1CYP2C19 | |
| SCHEMBL13622053 | 0.75 | PDK2 (0.38) | CYP2C19PDK2 | |
| SCHEMBL18052350 | 0.75 | PDK2 (0.38) | CYP2C19PDK2 | |
| SCHEMBL14207075 | 0.75 | PDK2 (0.35) | PDK2 | |
| SCHEMBL14207077 | 0.75 | PDK2 (0.35) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080091021-A1 | Diarylaminofluorene-based organometallic phosphors and organic light-emitting devices made with such compounds | HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY, THE (CN) | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080091021-A1 | Diarylaminofluorene-based organometallic phosphors and organic light-emitting devices made with such compounds | ORC3, MCM3, TEC | NPC1 4364/4885RAB9A 2955/4885KDM4E 1631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.