SCHEMBL13535489

SCHEMBL13535489

COCC(C)OC(C)COCC(C)OCc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
KMT2A Q03164 1/20 0.38
MAPT P10636 2/20 0.38
RCE1 Q9Y256 1/20 0.37
CA1 P00915 4/20 0.36
CA2 P00918 2/20 0.36
CA7 P43166 2/20 0.36
CA9 Q16790 2/20 0.36
TACR1 P25103 2/20 0.35
HTT P42858 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18427254 0.90 MAPT (0.43) TSHRKMT2AMAPTRCE1HTT
SCHEMBL3421389 0.90 MAPT (0.43) TSHRKMT2AMAPTRCE1HTT
SCHEMBL13535468 0.88 TSHR (0.48) TSHRKMT2ACA1CA2CA7
SCHEMBL13535486 0.86 MAPT (0.41) TSHRKMT2AMAPTRCE1HTT
SCHEMBL13535477 0.86 MAPT (0.41) TSHRKMT2AMAPTRCE1HTT
SCHEMBL13535474 0.85 KMT2A (0.44) TSHRKMT2AMAPTRCE1CA1
SCHEMBL5471268 0.83 TSHR (0.54) TSHRKMT2AMAPTCA1CA2
SCHEMBL28232944 0.81 TSHR (0.56) TSHRKMT2AMAPTCA1CA2
SCHEMBL4621117 0.81 TSHR (0.56) TSHRKMT2AMAPTCA1CA2
SCHEMBL27423007 0.80 TSHR (0.50) TSHRKMT2AMAPTCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7648651-B2 Solvent composition ADEKA CORPORATION (JP) 2010-01-19 US disclosed
US-7648651-B2 Solvent composition ADEKA CORPORATION (JP) 2010-01-19 US disclosed
US-20090093588-A1 Solvent Composition ADEKA CORPORATION (JP) 2009-04-09 US disclosed
US-20090093588-A1 Solvent Composition ADEKA CORPORATION (JP) 2009-04-09 US disclosed
US-7507355-B2 Solvent composition ADEKA CORPORATION (JP) 2009-03-24 US disclosed
US-7507355-B2 Solvent composition ADEKA CORPORATION (JP) 2009-03-24 US disclosed
US-20070257233-A1 Solvent Composition ADEKA CORPORATION (JP) 2007-11-08 US disclosed
US-20070257233-A1 Solvent Composition ADEKA CORPORATION (JP) 2007-11-08 US disclosed
EP-1808223-A1 SOLVENT COMPOSITION Adeka Corporation (JP) 2007-07-18 EP disclosed