SCHEMBL1353642

SCHEMBL1353642

c1ccc2c(c1)-c1ccc3c(c1-2)C1(c2ccccc2-3)c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
OPRK1 P41145 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
S100A4 P26447 1/20 0.36
PDK2 Q15119 11/20 0.35
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
THRB P10828 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
ATM Q13315 1/20 0.31
HSD17B10 Q99714 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
DNMT1 P26358 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38657604 0.82 KDM4E (0.43) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL10353267 0.80 PDK2 (0.45) MEN1LMNAMAPTKMT2ASMN1; SMN2
SCHEMBL29850254 0.78 THRB (0.38) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL5949152 0.78 MEN1 (0.46) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL5949283 0.77 DNMT1 (0.40) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL7099795 0.75 PDK2 (0.50) MEN1MAPTKMT2APDK2TDP1
SCHEMBL18374553 0.75 KMT2A (0.54) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL22435811 0.75 KMT2A (0.54) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL30284924 0.75 KMT2A (0.54) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL19530895 0.74 MEN1 (0.41) KDM4EMEN1LMNAMAPTOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8372942-B2 Polycarbonate resin, coating liquid containing same, and electrophotographic photosensitive body IDEMITSU KOSAN CO., LTD. (JP) 2013-02-12 US claimed
US-20110287354-A1 POLYCARBONATE RESIN, COATING LIQUID CONTAINING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY IDEMITSU KOSAN CO., LTD. (JP) 2011-11-24 US claimed
EP-2378363-A1 POLYCARBONATE RESIN, COATING LIQUID CONTAINING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY Idemitsu Kosan Co., Ltd. (JP) 2011-10-19 EP claimed
US-8372942-B2 Polycarbonate resin, coating liquid containing same, and electrophotographic photosensitive body IDEMITSU KOSAN CO., LTD. (JP) 2013-02-12 US disclosed
US-20110287354-A1 POLYCARBONATE RESIN, COATING LIQUID CONTAINING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY IDEMITSU KOSAN CO., LTD. (JP) 2011-11-24 US disclosed
EP-2378363-A1 POLYCARBONATE RESIN, COATING LIQUID CONTAINING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY Idemitsu Kosan Co., Ltd. (JP) 2011-10-19 EP disclosed