Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 3/20 | 0.52 |
| ▸ | GALR1 | P47211 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 5/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6791198 | 0.84 | CASP1 (0.57) | GALR2GALR1SRCHTR2CHTR2A | |
| SCHEMBL6797121 | 0.83 | GALR2 (0.54) | GALR2GALR1HTR2CHTR2ADRD2 | |
| SCHEMBL3247878 | 0.82 | GALR2 (0.52) | GALR2GALR1SRCHTR2CHTR2A | |
| SCHEMBL6790892 | 0.82 | GALR2 (0.52) | GALR2GALR1SRCHTR2CHTR2A | |
| SCHEMBL8263323 | 0.82 | GALR2 (0.59) | GALR2GALR1HTR2CHTR2AABCB1 | |
| SCHEMBL6788539 | 0.81 | GALR2 (0.54) | GALR2GALR1SRCHTR2CHTR2A | |
| SCHEMBL3240623 | 0.81 | GALR2 (0.52) | GALR2GALR1SRCHTR2CHTR2A | |
| SCHEMBL3242747 | 0.81 | GALR2 (0.60) | GALR2GALR1SRCHTR2CHTR2A | |
| SCHEMBL6895881 | 0.81 | GALR2 (0.49) | GALR2GALR1SRCHTR2CHTR2A | |
| SCHEMBL3244424 | 0.80 | GALR2 (0.51) | GALR2GALR1SRCHTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2140864-A2 | Use of GAL3 receptor antagonists for the treatment of depression and / or anxiety and compounds useful in such methods | H.Lundbeck A/S (DK) | 2010-01-06 | — | — | EP | disclosed |