Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PROC | P04070 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850028 | 0.80 | RIPK1 (0.49) | SMN1; SMN2RIPK1MMP8LMNARAB9A | |
| SCHEMBL24965924 | 0.77 | RIPK1 (0.51) | SMN1; SMN2RIPK1MMP8LMNARAB9A | |
| SCHEMBL21605451 | 0.77 | RIPK1 (0.51) | SMN1; SMN2RIPK1MMP8LMNARAB9A | |
| Hydrochloric Acid SCHEMBL10481433 | 0.75 | RIPK1 (0.50) | SMN1; SMN2RIPK1MMP8LMNARAB9A | |
| SCHEMBL3458542 | 0.73 | RIPK1 (0.45) | SMN1; SMN2RIPK1MMP8LMNARAB9A | |
| SCHEMBL21538589 | 0.72 | RIPK1 (0.47) | SMN1; SMN2RIPK1MMP8LMNARAB9A | |
| SCHEMBL21328307 | 0.72 | RIPK1 (0.47) | SMN1; SMN2RIPK1MMP8LMNARAB9A | |
| SCHEMBL3971356 | 0.71 | SLC6A4 (0.47) | SMN1; SMN2LMNARAB9ACYP2C19CYP1A2 | |
| SCHEMBL28634357 | 0.71 | RIPK1 (0.46) | SMN1; SMN2RIPK1MMP8LMNARAB9A | |
| SCHEMBL320060 | 0.70 | CA12 (0.52) | SMN1; SMN2RIPK1MMP8LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2548618-A2 | Organic compounds | Novartis AG (CH) | 2013-01-23 | — | — | EP | disclosed |
| WO-2010007046-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2010-01-21 | — | — | WO | disclosed |