Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13537188 | 0.88 | ROCK1 (0.44) | HDAC4HDAC7HDAC5CYP26A1MME | |
| SCHEMBL13537191 | 0.86 | HDAC4 (0.40) | HDAC4HDAC7HDAC5CYP26A1MME | |
| SCHEMBL13652981 | 0.81 | CPN1 (0.39) | RPS6KB1HDAC4SLC6A2SLC6A4 | |
| SCHEMBL13537183 | 0.79 | HDAC4 (0.44) | HDAC4HDAC7HDAC5CNR2CES2 | |
| SCHEMBL27766221 | 0.78 | RPS6KB1 (0.43) | RPS6KB1HDAC4HDAC7HDAC5CXCR1 | |
| SCHEMBL13075546 | 0.78 | RPS6KB1 (0.43) | RPS6KB1HDAC4HDAC7HDAC5CXCR1 | |
| SCHEMBL27745177 | 0.78 | RPS6KB1 (0.43) | RPS6KB1HDAC4HDAC7HDAC5CXCR1 | |
| SCHEMBL13075562 | 0.77 | RPS6KB1 (0.43) | RPS6KB1HDAC4HDAC7HDAC5CXCR1 | |
| SCHEMBL14338366 | 0.76 | HDAC4 (0.49) | RPS6KB1HDAC4HDAC7HDAC5CXCR1 | |
| SCHEMBL17465689 | 0.74 | RPS6KB1 (0.41) | RPS6KB1HDAC4HDAC7HDAC5CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7649015-B2 | Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| US-20070010489-A1 | Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds | GILEAD SCIENCES, INC. | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010489-A1 | Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds | PPA1, PNP, PPME1 | RPS6KB1 577/4885HDAC4 1277/4885HDAC7 1367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.