Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | HTR1A | P08908 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | HTR6 | P50406 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7480892 | 0.86 | NOS3 (0.68) | SLC6A4 | |
| SCHEMBL1122450 | 0.85 | NOS3 (0.70) | SLC6A4 | |
| SCHEMBL12306777 | 0.85 | SLC6A4 (0.64) | SLC6A4 | |
| SCHEMBL1122183 | 0.84 | SLC6A4 (0.63) | SLC6A4 | |
| SCHEMBL7485080 | 0.84 | SLC6A4 (0.65) | SLC6A4 | |
| SCHEMBL8607603 | 0.84 | SLC6A4 (0.77) | SLC6A4 | |
| SCHEMBL5367487 | 0.84 | SLC6A4 (0.76) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| SCHEMBL13323539 | 0.83 | SLC6A4 (1.00) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| SCHEMBL7478841 | 0.82 | SLC6A4 (0.63) | SLC6A4 | |
| SCHEMBL7484094 | 0.82 | NOS3 (0.83) | SLC6A4KDM4ELMNAPOLBHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |