Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PLK1 | P53350 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3904188 | 0.81 | PLK1 (0.50) | MAPK1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL3904192 | 0.81 | PLK1 (0.50) | MAPK1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL13537540 | 0.77 | KMT2A (0.43) | MAPK1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL13899634 | 0.74 | MAPK1 (0.57) | MAPK1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL12307052 | 0.70 | NPSR1 (0.44) | MAPK1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL12307050 | 0.68 | MEN1 (0.41) | MAPK1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL13537263 | 0.67 | MAPT (0.36) | MAPK1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL13537259 | 0.67 | MEN1 (0.38) | MAPK1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL3905980 | 0.66 | MAPT (0.48) | MAPK1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL6086787 | 0.64 | MAPT (0.46) | MAPK1MAPTMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |