Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11453791 | 0.76 | MAPK1 (0.50) | MAPK1LMNAHTTKMT2AMEN1 | |
| SCHEMBL13537423 | 0.74 | MAPK1 (0.36) | MAPK1LMNAHTTKMT2AMEN1 | |
| SCHEMBL3904188 | 0.71 | PLK1 (0.50) | MAPK1LMNAKMT2AMEN1POLB | |
| SCHEMBL3904192 | 0.71 | PLK1 (0.50) | MAPK1LMNAKMT2AMEN1POLB | |
| SCHEMBL9813583 | 0.64 | LMNA (0.45) | MAPK1LMNAHTTKMT2AMEN1 | |
| SCHEMBL15502247 | 0.63 | — | — | |
| SCHEMBL11223609 | 0.61 | MAPT (0.41) | KMT2AMEN1HSD17B10MAPTNPSR1 | |
| SCHEMBL10850946 | 0.61 | PSMD14 (0.48) | MAPK1LMNAHTTKMT2AMEN1 | |
| SCHEMBL181852 | 0.61 | — | — | |
| SCHEMBL9503508 | 0.60 | TSHR (0.43) | MAPK1KMT2AMEN1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511059-B2 | Thiazolidinones, their production and use as pharmaceutical agents | SCHERING AG (DE) | 2009-03-31 | — | — | US | disclosed |