Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3351301 | 0.81 | MEN1 (0.43) | MEN1KMT2AMAPTHSD17B10ALDH1A1 | |
| SCHEMBL13488670 | 0.81 | MEN1 (0.43) | MEN1KMT2AMAPTHSD17B10ALDH1A1 | |
| SCHEMBL13537262 | 0.80 | MEN1 (0.39) | MEN1KMT2AMAPTHSD17B10ALDH1A1 | |
| SCHEMBL13537540 | 0.77 | KMT2A (0.43) | MEN1KMT2AMAPTHSD17B10ALDH1A1 | |
| SCHEMBL13537259 | 0.77 | MEN1 (0.38) | MEN1KMT2AMAPTHSD17B10ALDH1A1 | |
| SCHEMBL13537354 | 0.75 | MAPT (0.34) | MEN1KMT2AMAPTHSD17B10ALDH1A1 | |
| SCHEMBL14622086 | 0.72 | MEN1 (0.35) | MEN1KMT2AMAPTHSD17B10ALDH1A1 | |
| SCHEMBL27608571 | 0.69 | MAPT (0.48) | MEN1KMT2AMAPTHSD17B10ALDH1A1 | |
| SCHEMBL14608231 | 0.66 | HTT (0.44) | MEN1KMT2AMAPTHSD17B10ALDH1A1 | |
| SCHEMBL3358918 | 0.63 | ALDH1A1 (0.49) | MEN1KMT2AMAPTHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |