SCHEMBL135377

SCHEMBL135377

CCCCCCCCCCc1[c]cc[c]c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 3/20 0.34
ESR1 P03372 2/20 0.34
ADRA2A P08913 2/20 0.34
ADORA3 P0DMS8 2/20 0.34
TACR2 P21452 2/20 0.34
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34
SLC6A3 Q01959 2/20 0.34
KCNH2 Q12809 2/20 0.34
HSD17B10 Q99714 2/20 0.34
ACHE P22303 2/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
SHBG P04278 1/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
HSPD1 P10809 1/20 0.34
ADRB3 P13945 1/20 0.34
HTR2C P28335 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7570539 1.00 PTGS2 (0.34) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL11787936 1.00 PTGS2 (0.34) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL1717389 1.00 PTGS2 (0.34) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL3423379 1.00 PTGS2 (0.34) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL1717457 1.00 PTGS2 (0.34) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL1717644 1.00 PTGS2 (0.34) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL2827738 1.00 PTGS2 (0.34) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL1717330 1.00 PTGS2 (0.34) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL2829246 0.98 PTGS2 (0.32) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL1499438 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240018308-A1 CURABLE SILICONE COMPOSITION AND CURED PRODUCT THEREOF DOW SILICONES CORP (US) 2024-01-18 US disclosed
US-20230366197-A1 Cementitious Panels with Swellable Materials and Methods of Providing a Moisture or Water Barrier in Cementitious Panels Using Swellable Materials BANK OF AMERICA, N.A., AS COLLATERAL AGENT 2023-11-16 US disclosed
US-11801662-B2 Cementitious panels with polymeric-film facing material GOLD BOND BUILDING PRODUCTS, LLC (US) 2023-10-31 US disclosed
EP-4222219-A1 CURABLE SILICONE COMPOSITION AND CURED PRODUCT THEREOF Dow Silicones Corporation (US) 2023-08-09 EP disclosed
US-11708692-B2 Cementitious panels with swellable materials and methods of providing a moisture or water barrier in cementitious panels using swellable materials GOLD BOND BUILDING PRODUCTS, LLC (US) 2023-07-25 US disclosed
CN-116075542-A Curable silicone composition and cured product thereof 美国陶氏有机硅公司 2023-05-05 CN disclosed
CN-113934112-A Protective film, photosensitive resin composition and display device 日铁化学材料株式会社 2022-01-14 CN disclosed
EP-3105053-B1 THIN NANOCOMPOSITE FILM FOR USE IN AN ABSORBENT ARTICLE KIMBERLY CLARK CO (US) 2021-09-22 EP disclosed
US-11058791-B2 Thin nanocomposite film for use in an absorbent article KIMBERLY-CLARK WORLDWIDE, INC. (US) 2021-07-13 US disclosed
CN-105939849-B Nanocomposite films for absorbent articles 金伯利-克拉克环球有限公司 2021-02-05 CN disclosed
US-20010033924-A1 Intercalates formed with polypropylene/maleic anhydride-modified polypropylene intercalants JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2001-10-25 US disclosed
US-20010025076-A1 Layered compositions with multi-charged onium ions as exchange cations, and their application to prepare monomer, oligomer, and polymer intercalates and nanocomposites prepared with the layered compositions of the intercalates AMCOL INTERNATIONAL CORPORATION 2001-09-27 US disclosed
US-6262162-B1 CAN BE USED AS ORGANOCLAYS FOR SORPTION OF ORGANIC MATERIALS, OR CAN BE DISPERSED UNIFORMLY INTO SOLVENTS TO INCREASE VISCOSITY OF ORGANIC LIQUIDS AMCOL INTERNATIONAL CORPORATION 2001-07-17 US disclosed
US-6232388-B1 CONTROLLING CONCENTRATION AMCOL INTERNATIONAL CORPORATION 2001-05-15 US disclosed
US-6225394-B1 USEFUL FOR BARRIER LAYERS IN MULTI-PACKAGING AND FOR COATINGS AMCOL INTERNATIONAL CORPORATION 2001-05-01 US disclosed
EP-1038834-A1 Surface modified layered silicate material and compositions containing the same AMCOL INTERNATIONAL CORPORATION (US) 2000-09-27 EP disclosed
WO-2000009605-A1 INTERCALATES FORMED WITH MXD6 NYLON INTERCALANTS AMCOL INTERNATIONAL CORPORATION (US) 2000-02-24 WO disclosed
EP-0835924-A1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION FOR DIESEL ENGINES Kao Corporation (JP) 1998-04-15 EP disclosed
US-3972851-A Preparation of polyphenylene oxide using a manganese(II) ortho-hydroxyarene-oxime chelate reaction promoter GENERAL ELECTRIC COMPANY (US) 1976-08-03 US disclosed
US-3965069-A Polyphenylene oxide is prepared using a mixture of manganese chelates as a catalyst GENERAL ELECTRIC COMPANY (US) 1976-06-22 US disclosed