Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | OGA | O60502 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506085 | 1.00 | LMNA (0.41) | LMNAGBA1TYRALDH1A1TSHR | |
| SCHEMBL8993561 | 1.00 | LMNA (0.41) | LMNAGBA1TYRALDH1A1TSHR | |
| SCHEMBL27288343 | 0.77 | LMNA (0.39) | LMNAGBA1 | |
| SCHEMBL28340362 | 0.77 | LMNA (0.39) | LMNAGBA1 | |
| SCHEMBL31490981 | 0.77 | LMNA (0.39) | LMNAGBA1OGA | |
| SCHEMBL30910036 | 0.77 | LMNA (0.39) | LMNAGBA1 | |
| SCHEMBL29005779 | 0.77 | LMNA (0.39) | LMNAGBA1OGA | |
| SCHEMBL12336503 | 0.77 | LMNA (0.39) | LMNAGBA1OGA | |
| SCHEMBL29377624 | 0.75 | LMNA (0.38) | LMNAGBA1OGA | |
| SCHEMBL31490979 | 0.75 | LMNA (0.38) | LMNAGBA1OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2145873-A1 | New compounds with activity that protects against the action of toxins and viruses in intracellular action mode | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2010-01-20 | — | — | EP | disclosed |