Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5941832 | 0.88 | ALDH1A1 (0.56) | ALDH1A1HSD17B10CYP2C19KDM4EUSP2 | |
| SCHEMBL1820208 | 0.88 | KDM4E (0.42) | ALDH1A1HSD17B10CYP2C19KDM4EUSP2 | |
| SCHEMBL16623994 | 0.88 | KDM4E (0.42) | ALDH1A1HSD17B10CYP2C19KDM4EUSP2 | |
| SCHEMBL1820204 | 0.88 | KDM4E (0.42) | ALDH1A1HSD17B10CYP2C19KDM4EUSP2 | |
| SCHEMBL5941812 | 0.82 | ALDH1A1 (0.54) | ALDH1A1HSD17B10CYP2C19KDM4EUSP2 | |
| SCHEMBL5941930 | 0.81 | CNR1 (0.45) | ALDH1A1HSD17B10CYP2C19KDM4EUSP2 | |
| SCHEMBL5942150 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CYP2C19KDM4EUSP2 | |
| SCHEMBL5942132 | 0.78 | ALDH1A1 (0.44) | ALDH1A1HSD17B10CYP2C19KDM4EUSP2 | |
| SCHEMBL16626063 | 0.78 | ALDH1A1 (0.47) | ALDH1A1HSD17B10CYP2C19KDM4EUSP2 | |
| SCHEMBL5941847 | 0.78 | CNR1 (0.41) | ALDH1A1HSD17B10CYP2C19KDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010006085-A1 | FATTY ACID ACETYLATED SALICYLATES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2010-01-14 | — | — | WO | disclosed |