Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3529423 | 1.00 | CCR5 (0.88) | CCR5KCNH2 | |
| SCHEMBL3526749 | 0.95 | CCR5 (0.85) | CCR5KCNH2 | |
| SCHEMBL13544066 | 0.93 | CCR5 (1.00) | CCR5KCNH2 | |
| SCHEMBL3526031 | 0.93 | CCR5 (1.00) | CCR5KCNH2 | |
| SCHEMBL3523282 | 0.93 | CCR5 (1.00) | CCR5KCNH2 | |
| SCHEMBL13543126 | 0.93 | CCR5 (0.89) | CCR5KCNH2 | |
| SCHEMBL3529225 | 0.93 | CCR5 (0.89) | CCR5KCNH2 | |
| SCHEMBL3526647 | 0.93 | KCNH2 (1.00) | CCR5KCNH2 | |
| SCHEMBL13544261 | 0.93 | KCNH2 (1.00) | CCR5KCNH2 | |
| SCHEMBL3524953 | 0.92 | CCR5 (0.88) | CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645771-B2 | CCR5 antagonists as therapeutic agents | SMITHKLINE BEECHAM CORP. (US) | 2010-01-12 | — | — | US | disclosed |
| US-7645771-B2 | CCR5 antagonists as therapeutic agents | SMITHKLINE BEECHAM CORP. (US) | 2010-01-12 | — | — | US | disclosed |