Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 11/20 | 0.80 |
| ▸ | CA12 | O43570 | 10/20 | 0.75 |
| ▸ | CA1 | P00915 | 10/20 | 0.75 |
| ▸ | CA2 | P00918 | 10/20 | 0.75 |
| ▸ | CA6 | P23280 | 9/20 | 0.75 |
| ▸ | CA7 | P43166 | 9/20 | 0.75 |
| ▸ | CA14 | Q9ULX7 | 9/20 | 0.75 |
| ▸ | CA9 | Q16790 | 9/20 | 0.75 |
| ▸ | CA5B | Q9Y2D0 | 8/20 | 0.75 |
| ▸ | CA3 | P07451 | 8/20 | 0.75 |
| ▸ | CA13 | Q8N1Q1 | 8/20 | 0.75 |
| ▸ | CA5A | P35218 | 8/20 | 0.75 |
| ▸ | CA4 | P22748 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.56 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.56 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1716052 | 0.89 | CISD1 (1.00) | CISD1CA12CA1CA2CA6 | |
| SCHEMBL18425099 | 0.87 | CISD1 (0.78) | CISD1CA12CA1CA2CA6 | |
| SCHEMBL13543235 | 0.87 | CISD1 (0.78) | CISD1CA12CA1CA2CA6 | |
| SCHEMBL18424857 | 0.86 | CA1 (1.00) | CISD1CA12CA1CA2CA6 | |
| SCHEMBL31670531 | 0.86 | CA1 (1.00) | CISD1CA12CA1CA2CA6 | |
| SCHEMBL18424482 | 0.84 | CA12 (1.00) | CISD1CA12CA1CA2CA6 | |
| SCHEMBL13545222 | 0.82 | CISD1 (0.80) | CISD1CA12CA1CA2CA6 | |
| SCHEMBL18425356 | 0.82 | CA12 (1.00) | CISD1CA12CA1CA2CA6 | |
| SCHEMBL18425147 | 0.82 | CA1 (1.00) | CISD1CA12CA1CA2CA6 | |
| SCHEMBL12418658 | 0.81 | CISD1 (0.81) | CISD1CA12CA1CA2CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645771-B2 | CCR5 antagonists as therapeutic agents | SMITHKLINE BEECHAM CORP. (US) | 2010-01-12 | — | — | US | disclosed |