Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 20/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10299818 | 0.92 | TRPM8 (1.00) | TRPM8 | |
| SCHEMBL1098880 | 0.92 | TRPM8 (1.00) | TRPM8 | |
| SCHEMBL10299803 | 0.92 | TRPM8 (1.00) | TRPM8 | |
| SCHEMBL10299817 | 0.92 | TRPM8 (1.00) | TRPM8 | |
| SCHEMBL1100110 | 0.91 | TRPM8 (0.98) | TRPM8 | |
| SCHEMBL1099268 | 0.90 | TRPM8 (1.00) | TRPM8 | |
| SCHEMBL10299870 | 0.89 | TRPM8 (0.79) | TRPM8 | |
| SCHEMBL1107191 | 0.88 | TRPM8 (0.89) | TRPM8 | |
| SCHEMBL1097923 | 0.88 | TRPM8 (0.77) | TRPM8 | |
| SCHEMBL1099918 | 0.87 | TRPM8 (0.79) | TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010009220-A2 | RADIOLABELLED TRP M8 RECEPTOR LIGANDS | JANSSEN PHARMACEUTICA NV (BE) | 2010-01-21 | — | — | WO | disclosed |