Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 6/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6279104 | 0.86 | ALDH1A1 (0.70) | ALDH1A1HSD17B10SMN1; SMN2MAPTHPGD | |
| SCHEMBL859415 | 0.85 | ALDH1A1 (0.74) | ALDH1A1HSD17B10SMN1; SMN2MAPTHPGD | |
| SCHEMBL6281848 | 0.83 | ALDH1A1 (0.65) | ALDH1A1HSD17B10SMN1; SMN2MAPTHPGD | |
| SCHEMBL6278534 | 0.83 | ALDH1A1 (0.65) | ALDH1A1HSD17B10SMN1; SMN2MAPTHPGD | |
| SCHEMBL6277599 | 0.83 | ALDH1A1 (0.65) | ALDH1A1HSD17B10SMN1; SMN2MAPTHPGD | |
| SCHEMBL6278157 | 0.83 | KMT2A (0.66) | ALDH1A1HSD17B10SMN1; SMN2MAPTHPGD | |
| SCHEMBL6274384 | 0.83 | ALDH1A1 (0.64) | ALDH1A1HSD17B10SMN1; SMN2MAPTHPGD | |
| SCHEMBL1702494 | 0.83 | ALDH1A1 (0.64) | ALDH1A1HSD17B10SMN1; SMN2MAPTHPGD | |
| SCHEMBL6412016 | 0.82 | ALDH1A1 (0.64) | ALDH1A1HSD17B10SMN1; SMN2MAPTHPGD | |
| SCHEMBL859751 | 0.82 | ALDH1A1 (1.00) | ALDH1A1HSD17B10SMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642277-B2 | Non-nucleoside reverse transcriptase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-01-05 | — | — | US | disclosed |