Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4154416 | 0.83 | TSHR (0.47) | GAANPC1GLATSHRALDH1A1 | |
| SCHEMBL383766 | 0.81 | GAA (0.54) | GAANPC1TAAR1GLATSHR | |
| SCHEMBL7136324 | 0.81 | ACHE (0.42) | GAATAAR1TSHRACHEALDH1A1 | |
| SCHEMBL24307238 | 0.79 | TAAR1 (0.45) | GAATAAR1GLAACHEALDH1A1 | |
| SCHEMBL1755249 | 0.79 | NPC1 (0.58) | GAANPC1TAAR1GLATSHR | |
| SCHEMBL92052 | 0.79 | GAA (0.52) | GAANPC1TAAR1GLATSHR | |
| SCHEMBL4179556 | 0.77 | GAA (0.50) | GAANPC1TAAR1TSHRALDH1A1 | |
| SCHEMBL6743305 | 0.77 | NPC1 (0.56) | GAANPC1TAAR1ALDH1A1NPSR1 | |
| SCHEMBL30920447 | 0.77 | NPC1 (0.67) | GAANPC1TAAR1TSHRALDH1A1 | |
| SCHEMBL27731924 | 0.77 | NPC1 (0.45) | GAANPC1TAAR1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642277-B2 | Non-nucleoside reverse transcriptase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-01-05 | — | — | US | disclosed |