Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 19/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1449982 | 0.89 | GPR119 (0.63) | GPR119CYP2C9CYP3A4 | |
| SCHEMBL2372308 | 0.87 | GPR119 (0.63) | GPR119CYP2C9CYP3A4 | |
| SCHEMBL11913106 | 0.86 | GPR119 (0.62) | GPR119CYP2C9CYP3A4 | |
| SCHEMBL11913061 | 0.81 | GPR119 (0.62) | GPR119CYP2C9CYP3A4 | |
| SCHEMBL12596422 | 0.81 | GPR119 (0.66) | GPR119CYP2C9CYP3A4 | |
| SCHEMBL10137743 | 0.81 | GPR119 (0.66) | GPR119CYP2C9CYP3A4 | |
| SCHEMBL10171813 | 0.81 | GPR119 (0.66) | GPR119CYP2C9CYP3A4 | |
| SCHEMBL303668 | 0.81 | CYP2C9 (0.80) | GPR119CYP2C9CYP3A4 | |
| SCHEMBL10137710 | 0.81 | GPR119 (0.81) | GPR119CYP2C9CYP3A4 | |
| SCHEMBL11317271 | 0.80 | GPR119 (1.00) | GPR119CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010009207-A1 | BICYCLIC HETEROCYCLE DERIVATIVES AND THEIR USE AS GPCR MODULATORS | SCHERING CORPORATION (US) | 2010-01-21 | — | — | WO | disclosed |