Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 15/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.42 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13118135 | 0.88 | FFAR1 (0.48) | FFAR1MRGPRX4PPARDNR1H2NR1H3 | |
| SCHEMBL13548835 | 0.88 | FFAR1 (0.55) | FFAR1MRGPRX4PPARD | |
| SCHEMBL13118134 | 0.88 | FFAR1 (0.52) | FFAR1MRGPRX4PPARDNR1H2NR1H3 | |
| SCHEMBL13118136 | 0.88 | FFAR1 (0.50) | FFAR1MRGPRX4PPARDNR1H2NR1H3 | |
| SCHEMBL13118139 | 0.87 | FFAR1 (0.49) | FFAR1MRGPRX4PPARDNR1H2NR1H3 | |
| SCHEMBL13118141 | 0.86 | FFAR1 (0.48) | FFAR1MRGPRX4PPARDNR1H2NR1H3 | |
| SCHEMBL3520902 | 0.80 | FFAR1 (0.61) | FFAR1MRGPRX4PPARDNR1H2NR1H3 | |
| SCHEMBL3523470 | 0.79 | FFAR1 (0.66) | FFAR1MRGPRX4PPARDNR1H2NR1H3 | |
| SCHEMBL3520170 | 0.79 | FFAR1 (0.62) | FFAR1MRGPRX4PPARDNR1H2NR1H3 | |
| SCHEMBL3519034 | 0.77 | FFAR1 (0.60) | FFAR1MRGPRX4PPARDNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7649110-B2 | Compounds, pharmaceutical compositions and methods for use in treating metabolic disorders | AMGEN INC. (US) | 2010-01-19 | — | — | US | disclosed |