Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 19/20 | 0.55 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13548833 | 0.88 | FFAR1 (0.47) | FFAR1PPARDMRGPRX4 | |
| SCHEMBL13118137 | 0.87 | FFAR1 (0.59) | FFAR1PPARDMRGPRX4 | |
| SCHEMBL3525795 | 0.77 | FFAR1 (0.88) | FFAR1PPARDMRGPRX4 | |
| SCHEMBL13118134 | 0.77 | FFAR1 (0.52) | FFAR1PPARDMRGPRX4 | |
| SCHEMBL13550339 | 0.77 | FFAR1 (0.74) | FFAR1PPARDMRGPRX4 | |
| SCHEMBL13550323 | 0.76 | FFAR1 (0.79) | FFAR1PPARDMRGPRX4 | |
| SCHEMBL13118135 | 0.76 | FFAR1 (0.48) | FFAR1PPARDMRGPRX4 | |
| SCHEMBL13118136 | 0.75 | FFAR1 (0.50) | FFAR1PPARDMRGPRX4 | |
| SCHEMBL13140189 | 0.74 | FFAR1 (0.79) | FFAR1MRGPRX4 | |
| SCHEMBL13118336 | 0.74 | FFAR1 (0.76) | FFAR1PPARDMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7649110-B2 | Compounds, pharmaceutical compositions and methods for use in treating metabolic disorders | AMGEN INC. (US) | 2010-01-19 | — | — | US | disclosed |