Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.59 |
| ▸ | CKS1B | P61024 | 1/20 | 0.44 |
| ▸ | SKP1 | P63208 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9431190 | 0.82 | TDP1 (0.52) | EPHX1CKS1BSKP1SKP2ALDH1A1 | |
| SCHEMBL3324608 | 0.81 | CKS1B (0.43) | EPHX1EPHX2CKS1BSKP1SKP2 | |
| SCHEMBL3218529 | 0.81 | CKS1B (0.43) | EPHX1EPHX2CKS1BSKP1SKP2 | |
| SCHEMBL11909488 | 0.81 | CKS1B (0.43) | EPHX1EPHX2CKS1BSKP1SKP2 | |
| SCHEMBL6403172 | 0.79 | KDM4E (0.60) | EPHX1KDM1ASMN1; SMN2KDM4EPKM | |
| SCHEMBL3381027 | 0.78 | HDAC6 (0.53) | EPHX1CKS1BSKP1SKP2ALDH1A1 | |
| SCHEMBL3383177 | 0.78 | HDAC6 (0.49) | EPHX1CKS1BSKP1SKP2ALDH1A1 | |
| SCHEMBL3522643 | 0.78 | CKS1B (0.43) | EPHX1EPHX2CKS1BSKP1SKP2 | |
| SCHEMBL4577744 | 0.77 | EPHX1 (0.48) | EPHX1EPHX2KDM1A | |
| SCHEMBL4577748 | 0.77 | EPHX1 (0.48) | EPHX1EPHX2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645774-B2 | Cannabinoid receptor ligands | SCHERING CORPORATION (US) | 2010-01-12 | — | — | US | disclosed |