Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.43 |
| ▸ | SKP1 | P63208 | 2/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4007514 | 0.86 | CACNA1H (0.38) | CKS1BSKP1SKP2EPHX1EPHX2 | |
| SCHEMBL9431190 | 0.79 | TDP1 (0.52) | CKS1BSKP1SKP2EPHX1ALDH1A1 | |
| SCHEMBL3529302 | 0.78 | MGLL (0.36) | EPHX1EPHX2KCNH2SIRT2SIRT1 | |
| SCHEMBL13549321 | 0.78 | EPHX1 (0.59) | CKS1BSKP1SKP2EPHX1EPHX2 | |
| SCHEMBL6403172 | 0.77 | KDM4E (0.60) | EPHX1KDM4EPKMSMN1; SMN2GNRHR | |
| SCHEMBL4014367 | 0.76 | SIRT2 (0.40) | ALDH1A1NQO2MTNR1AMTNR1BACHE | |
| SCHEMBL3383177 | 0.76 | HDAC6 (0.49) | CKS1BSKP1SKP2EPHX1ALDH1A1 | |
| SCHEMBL3381027 | 0.76 | HDAC6 (0.53) | CKS1BSKP1SKP2EPHX1ALDH1A1 | |
| SCHEMBL3379859 | 0.74 | HDAC6 (0.55) | EPHX1ALDH1A1POLBSMN1; SMN2HDAC6 | |
| SCHEMBL5560105 | 0.74 | ENPP2 (0.32) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645774-B2 | Cannabinoid receptor ligands | SCHERING CORPORATION (US) | 2010-01-12 | — | — | US | disclosed |
| US-7071213-B2 | Cannabinoid receptor ligands | SCHERING CORPORATION (US) | 2006-07-04 | — | — | US | disclosed |
| US-20050282861-A1 | Cannabinoid receptor ligands | MERCK SHARP & DOHME CORP. | 2005-12-22 | — | — | US | disclosed |
| EP-1444203-A1 | CANNABINOID RECEPTOR LIGANDS | Schering Corporation (US) | 2004-08-11 | — | — | EP | disclosed |
| US-20040010013-A1 | Piperidine derivatives used in treating cancer, inflammatory diseases, immunomodulatory diseases, or respiratory diseases | SCHERING CORPORATION | 2004-01-15 | — | — | US | disclosed |
| WO-2003042174-A1 | CANNABINOID RECEPTOR LIGANDS | SCHERING CORPORATION (US) | 2003-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040010013-A1 | Piperidine derivatives used in treating cancer, inflammatory diseases, immunomodulatory diseases, or respiratory diseases | IL5, IL2, TLR1 | CKS1B 4151/4885SKP1 1328/4885SKP2 2085/4885 |
| US-20050282861-A1 | Cannabinoid receptor ligands | CNR1, CNR2, GPR18 | CKS1B 1968/4885SKP1 3795/4885SKP2 4356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.