Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.72 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 7/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.43 |
| ▸ | MAOA | P21397 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13551443 | 0.89 | APP (0.65) | APPPTGER4KDM4ENPC1ALDH1A1 | |
| SCHEMBL13551425 | 0.89 | APP (0.71) | APPPTGER4KDM4ENPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27894975 | 0.88 | APP (0.62) | APPPTGER4KDM4ENPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL13387382 | 0.88 | APP (0.73) | APPPTGER4KDM4ENPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL13387384 | 0.88 | APP (0.73) | APPPTGER4KDM4ENPC1ALDH1A1 | |
| SCHEMBL13551414 | 0.85 | APP (0.98) | APPPTGER4KDM4ENPC1ALDH1A1 | |
| Iodide SCHEMBL13387784 | 0.84 | APP (0.75) | APPPTGER4KDM4ENPC1ALDH1A1 | |
| Iodide SCHEMBL13387783 | 0.84 | APP (0.75) | APPPTGER4KDM4ENPC1ALDH1A1 | |
| Iodide SCHEMBL13387358 | 0.84 | APP (1.00) | APPPTGER4KDM4ENPC1ALDH1A1 | |
| Iodide SCHEMBL13387357 | 0.84 | APP (1.00) | APPPTGER4KDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9795694-B2 | Imaging beta-amyloid peptides aggregation | HONG KONG BAPTIST UNIVERSITY (HK) | 2017-10-24 | — | — | US | disclosed |
| US-20160243264-A1 | Imaging Beta-Amyloid Peptides Aggregation | HONG KONG BAPTIST UNIVERSITY (HK) | 2016-08-25 | — | — | US | disclosed |
| US-9403794-B2 | Imaging beta-amyloid peptides and inhibition of beta-amyloid peptide aggregation | HONG KONG BAPTIST UNIVERSITY (HK) | 2016-08-02 | — | — | US | disclosed |
| US-9255933-B2 | Imaging beta-amyloid peptides and inhibition of beta-amyloid peptide aggregation | HONG KONG BAPTIST UNIVERSITY (HK) | 2016-02-09 | — | — | US | disclosed |
| US-9156814-B2 | Imaging beta-amyloid peptides and inhibition of beta-amyloid peptide aggregation | HONG KONG BAPTIST UNIVERSITY (HK) | 2015-10-13 | — | — | US | disclosed |
| US-20140213614-A1 | Imaging Beta-Amyloid Peptides and Inhibition of Beta-Amyloid Peptide Aggregation | HONG KONG BAPTIST UNIVERSITY (HK) | 2014-07-31 | — | — | US | disclosed |
| US-20140212360-A1 | Imaging Beta-Amyloid Peptides and Inhibition of Beta-Amyloid Peptide Aggregation | HONG KONG BAPTIST UNIVERSITY (HK) | 2014-07-31 | — | — | US | disclosed |
| US-20120269738-A1 | Imaging Beta-Amyloid Peptides and Inhibition of Beta-Amyloid Peptide Aggregation | HONG KONG BAPTIST UNIVERSITY (HK) | 2012-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120269738-A1 | Imaging Beta-Amyloid Peptides and Inhibition of Beta-Amyloid Peptide Aggregation | APP, IAPP, BACE1 | APP 1/4885PTGER4 4506/4885KDM4E 4808/4885 |
| US-20140213614-A1 | Imaging Beta-Amyloid Peptides and Inhibition of Beta-Amyloid Peptide Aggregation | APP, IAPP, BACE1 | APP 1/4885PTGER4 4252/4885KDM4E 4811/4885 |
| US-20160243264-A1 | Imaging Beta-Amyloid Peptides Aggregation | APP, IAPP, APBA1 | APP 1/4885PTGER4 4526/4885KDM4E 4078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.