SCHEMBL13552106

SCHEMBL13552106

Cc1cn([C@H]2C[C@@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c2ncnc(N)c12

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ DTYMK P23919 4/20 0.59
▸ POLB P06746 2/20 0.56
▸ TRPM2 O94759 1/20 0.53
▸ P2RY1 P47900 4/20 0.51
▸ ENPP1 P22413 2/20 0.51
▸ P2RX1 P51575 3/20 0.51
▸ P2RX3 P56373 3/20 0.51
▸ P2RX2 Q9UBL9 2/20 0.51
▸ CA2 P00918 1/20 0.50
▸ P2RY2 P41231 2/20 0.48
▸ P2RX4 Q99571 2/20 0.48
▸ SRC P12931 1/20 0.48
▸ ALDH1A1 P00352 1/20 0.48
▸ SMN1; SMN2 Q16637 1/20 0.48
▸ PRMT5 O14744 1/20 0.48
▸ METTL3 Q86U44 1/20 0.48
▸ RNASEL Q05823 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13654813 1.00 DTYMK (0.59) DTYMKPOLBTRPM2P2RY1ENPP1
SCHEMBL18852775 1.00 DTYMK (0.59) DTYMKPOLBTRPM2P2RY1ENPP1
SCHEMBL12932267 1.00 DTYMK (0.59) DTYMKPOLBTRPM2P2RY1ENPP1
SCHEMBL23236495 0.89 POLB (0.56) DTYMKPOLBTRPM2P2RY1ENPP1
SCHEMBL6062467 0.89 POLB (0.56) DTYMKPOLBTRPM2P2RY1ENPP1
SCHEMBL20906732 0.89 POLB (0.56) DTYMKPOLBTRPM2P2RY1ENPP1
SCHEMBL10051912 0.89 POLB (0.58) DTYMKPOLBTRPM2P2RY1ENPP1
SCHEMBL19033185 0.89 POLB (0.60) DTYMKPOLBTRPM2P2RY1ENPP1
SCHEMBL17702009 0.85 POLB (0.54) DTYMKPOLBTRPM2P2RY1ENPP1
SCHEMBL30002736 0.85 POLB (0.51) DTYMKPOLBTRPM2P2RY1ENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8853373-B2 Method and reagent for gene sequence analysis HITACHI, LTD. (JP) 2014-10-07 — — US disclosed
US-20120270210-A1 METHOD AND REAGENT FOR GENE SEQUENCE ANALYSIS HITACHI, LTD. (JP) 2012-10-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120270210-A1 METHOD AND REAGENT FOR GENE SEQUENCE ANALYSIS RNGTT, DNTT, MTAP DTYMK 9/4885POLB 56/4885TRPM2 4557/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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