RNGTT

mRNA-capping enzyme · O60942 · RNGTT on Sugi Atlas →

1,892 patent compounds predicted against RNGTT, 1,675 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
Molibresib Molibresib (SCHEMBL1872390) 1.00 1/20
Molibresib Molibresib (SCHEMBL12671490) 1.00 1/20
Molibresib Molibresib (SCHEMBL12966358) 1.00 1/20
SCHEMBL9998851 SCHEMBL9998851 0.91 1/20
SCHEMBL14756282 SCHEMBL14756282 0.88 1/20
SCHEMBL15980874 SCHEMBL15980874 0.88 1/20
SCHEMBL12966165 SCHEMBL12966165 0.87 1/20
SCHEMBL14756215 SCHEMBL14756215 0.87 1/20
SCHEMBL14756339 SCHEMBL14756339 0.87 1/20
SCHEMBL15980861 SCHEMBL15980861 0.87 1/20
SCHEMBL9998825 SCHEMBL9998825 0.86 1/20
SCHEMBL15980893 SCHEMBL15980893 0.86 1/20
SCHEMBL15980803 SCHEMBL15980803 0.86 1/20
SCHEMBL1874116 SCHEMBL1874116 0.85 1/20
SCHEMBL12671221 SCHEMBL12671221 0.85 1/20
SCHEMBL14756021 SCHEMBL14756021 0.85 1/20
SCHEMBL14756240 SCHEMBL14756240 0.85 1/20
SCHEMBL14756287 SCHEMBL14756287 0.85 1/20
SCHEMBL14756335 SCHEMBL14756335 0.85 1/20
SCHEMBL14756409 SCHEMBL14756409 0.85 1/20

Clinical trials — most relevant to RNGTT by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effects of Exercise Training on Systemic Inflammation an Muscle Repair According to the Obstructive Chronic Pulmonary Disease (COPD) Phenotype PHASE4UNKNOWN
Clinical Study of EBV-LMP1 Targeted DNAzyme to Treat Nasopharyngeal Carcinoma PHASE1/PHASE2COMPLETED
A Phase 1/2 Study of STP938 (Dencatistat) for Adult Subjects With Relapsed/Refractory B-Cell and T-Cell Lymphomas PHASE1/PHASE2RECRUITING
Safety and Efficacy Study of Small Interfering RNA Molecule (Cand5) to Treat Diabetic Macular Edema PHASE2COMPLETED
Combination Chemotherapy in Treating Patients With Previously Untreated Stage II or Stage III Esophageal Cancer That Can Be Removed By Surgery PHASE2COMPLETED
Liver Resection and Floxuridine Plus Fluorouracil and Leucovorin in Treating Patients With Liver Metastases From Colorectal Cancer PHASE2COMPLETED
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
Pilot Study on Molecular Quantitation and Sequencing of Endometrial Cytokines Gene Expression and Their Effect on the Outcome of In-vitro Fertilization (IVF) Cycle nanUNKNOWN
Methylation of DNA in Children and Adolescents With Type 1 Diabetes Mellitus (METHYLDIAB) nanCOMPLETED
The Value of circRNAs (hsa_circ_0004001) in Early Diagnosis of HCC nanUNKNOWN
Using the Epitranscriptome to Diagnose and Treat Gliomas nanRECRUITING
Determination of the Effectiveness of Oral Chlorine Dioxide in the Treatment of COVID 19 nanUNKNOWN
Investigation of the Genetic and Environmental Causes of Autism: a Multi-Center Study nanNOT_YET_RECRUITING
The Molecular Pathogenesis Study of Cataract nanUNKNOWN
Effect of DNMT SNPs on DNA Methylation in Primary ITP nanUNKNOWN
Role of Multiplex PCR in CAP nanUNKNOWN
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
RNA Sequencing in the Framingham Heart Study Third Generation Cohort Exam 2 nanCOMPLETED
Efficacy of a Multiplex BangasureTM RT-PCR Kit for the Detection of COVID-19 nanCOMPLETED
Epitranscriptomic Blood Biomarkers for Coronary Artery Disease - A Prospective Cohort Study (IHD-EPITRAN) nanUNKNOWN
Study of Specimens From Young Patients With Neuroblastoma nanCOMPLETED
Markers in Acute Pancreatitis-1 nanCOMPLETED
The Effect of Ca(OH)2 in Apical Periodontitis nanCOMPLETED
miR-155 Expression in Episodic and Chronic Migraine nanUNKNOWN
The Role of Circulating CircRNAs and MicroRNAs in Acute Lung Injury nanUNKNOWN
Effect of Branched Chain Amino Acids on Muscle nanCOMPLETED
Timisnar - Biomarkers Substudy (Timisnar-mirna) nanUNKNOWN
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis nanCOMPLETED
Inhibition of SENP1 for the Suppression of OS Growth and Metastasis nanUNKNOWN
Search for Bovine miRNA Transference to Humans nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a RNGTT binder may also engage these)

ProteinNameSimilarity
O55236 1.000 O55236 →
Q6NY98 0.995 Q6NY98 →
A0FKG7 0.971 A0FKG7 →
P97789 0.970 P97789 →
Q8IZH2 0.970 Q8IZH2 →
Q5R8R4 0.968 Q5R8R4 →
Q9Y6W3 0.968 Q9Y6W3 →
Q4V7N2 0.966 Q4V7N2 →
Q9QW07 0.966 Q9QW07 →
Q64514 0.966 Q64514 →
UBA2 SUMO-activating enzyme subunit 2 0.966 landscape →
Q5ZKY2 0.966 Q5ZKY2 →
Q9R1S8 0.965 Q9R1S8 →
MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 0.965 landscape →
Q6NYU2 0.965 Q6NYU2 →
Q9Z1F9 0.964 Q9Z1F9 →
O08586 0.964 O08586 →
ERCC4 DNA repair endonuclease XPF (EC 3.1.-.-) (DNA 0.964 landscape →
Q9LL84 0.964 Q9LL84 →
TPP2 Tripeptidyl-peptidase 2 0.963 landscape →
Q5XGS8 0.963 Q5XGS8 →
Q8IWV8 0.963 Q8IWV8 →
PTEN Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 0.963 landscape →
Q8BPM2 0.963 Q8BPM2 →
O55091 0.962 O55091 →
Q5RGJ5 0.962 Q5RGJ5 →
Q8QFR2 0.962 Q8QFR2 →
Q1HFZ0 0.962 Q1HFZ0 →
O54857 0.962 O54857 →
PLCB1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 0.962 landscape →