Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.34 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL755357 | 0.80 | CUL4A (0.33) | CES1ALDH1A1CUL4APSMB5PSMB1 | |
| SCHEMBL17512273 | 0.79 | HDAC6 (0.45) | ALDH1A1PSMB5 | |
| SCHEMBL24803269 | 0.77 | GRIN2B (0.42) | — | |
| SCHEMBL16144682 | 0.77 | CASP3 (0.42) | ALDH1A1PSMB5GAA | |
| SCHEMBL2536105 | 0.76 | PIK3CD (0.40) | ALDH1A1GAAHTR2AHTR2C | |
| SCHEMBL13837758 | 0.74 | GSK3A (0.45) | ALDH1A1L3MBTL1 | |
| SCHEMBL21218000 | 0.73 | SMN1; SMN2 (0.51) | ALDH1A1PSMB5PSMB1GAANTSR1 | |
| SCHEMBL18186968 | 0.73 | ACACB (0.39) | GAA | |
| SCHEMBL115654 | 0.72 | CYP2C19 (0.35) | GAA | |
| SCHEMBL20705071 | 0.72 | HSP90AA1 (0.31) | GAAHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011314-A1 | CYCLIC INHIBITORS OF 11 BETA-HYDROXYSTEROID DEHYDROGENASE 1 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-01-28 | — | — | WO | disclosed |