SCHEMBL1355227

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1355878	0.92	EIF2AK4 (0.49)	CDK4CCND1CCND2CCND3EIF2AK4
	SCHEMBL1355944	0.89	EIF2AK4 (0.52)	CDK4CCND1CCND2CCND3EIF2AK4
	SCHEMBL1355858	0.86	EIF2AK4 (0.61)	CDK4CCND1CCND2CCND3EIF2AK4
	SCHEMBL1355130	0.85	EIF2AK4 (0.50)	CDK4CCND1CCND2CCND3EIF2AK4
	SCHEMBL1355283	0.85	EIF2AK4 (0.52)	CDK4EIF2AK4AURKAKDM4EMAPT
	SCHEMBL1353652	0.84	CDK4 (0.54)	CDK4CCND1CCND2CCND3EIF2AK4
	SCHEMBL1356097	0.82	MAPT (0.52)	CDK4CCND1CCND2CCND3EIF2AK4
	SCHEMBL3582215	0.82	CDK4 (0.46)	CDK4CCND1CCND2CCND3EIF2AK4
	SCHEMBL1356726	0.81	RPS6KA3 (0.45)	EIF2AK4PLK1SYKRPS6KA3EGFR
	SCHEMBL1353618	0.81	EIF2AK4 (0.62)	EIF2AK4AURKBAURKAKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.