Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.73 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.73 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.73 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.73 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.73 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 8/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | PTGFR | P43088 | 2/20 | 0.31 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13386615 | 0.94 | PTGIR (0.75) | PTGIRPTGER3PTGER1PTGER2PTGDR | |
| SCHEMBL13386616 | 0.94 | PTGIR (0.75) | PTGIRPTGER3PTGER1PTGER2PTGDR | |
| SCHEMBL12951630 | 0.93 | PTGIR (0.71) | PTGIRPTGER3PTGER1PTGER2PTGDR | |
| SCHEMBL13554236 | 0.91 | PTGIR (0.77) | PTGIRPTGER3PTGER1PTGER2PTGDR | |
| SCHEMBL13554232 | 0.89 | PTGIR (0.75) | PTGIRPTGER3PTGER1PTGER2PTGDR | |
| SCHEMBL13386552 | 0.88 | PTGIR (0.79) | PTGIRPTGER3PTGER1PTGER2PTGDR | |
| SCHEMBL13386555 | 0.88 | PTGIR (0.79) | PTGIRPTGER3PTGER1PTGER2PTGDR | |
| SCHEMBL13386556 | 0.88 | PTGIR (0.79) | PTGIRPTGER3PTGER1PTGER2PTGDR | |
| SCHEMBL12951629 | 0.88 | PTGIR (0.79) | PTGIRPTGER3PTGER1PTGER2PTGDR | |
| SCHEMBL13554227 | 0.88 | PTGIR (0.77) | PTGIRPTGER3PTGER1PTGER2PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120270934-A1 | PROSTACYCLIN DERIVATIVES | CONCERT PHARMACEUTICALS, INC. | 2012-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270934-A1 | PROSTACYCLIN DERIVATIVES | PTGIS, PTGIR, PTGER1 | PTGIR 2/4885PTGER3 7/4885PTGER1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.