Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 16/20 | 0.46 |
| ▸ | PGR | P06401 | 14/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13797568 | 0.82 | AR (0.48) | ARPGRNR3C2LMNAMAPT | |
| SCHEMBL13473568 | 0.73 | AR (0.49) | ARPGRNR3C2LMNAMEN1 | |
| SCHEMBL925264 | 0.69 | AR (0.53) | ARPGRNR3C2LMNAMEN1 | |
| SCHEMBL922851 | 0.69 | AR (0.53) | ARPGRNR3C2LMNAMEN1 | |
| SCHEMBL924006 | 0.69 | AR (0.53) | ARPGRNR3C2LMNAMEN1 | |
| SCHEMBL924827 | 0.69 | AR (0.53) | ARPGRNR3C2LMNAMEN1 | |
| SCHEMBL7700801 | 0.69 | AR (0.58) | ARPGRNR3C2LMNAMAPT | |
| SCHEMBL6836545 | 0.69 | AR (0.58) | ARPGRNR3C2LMNAMAPT | |
| SCHEMBL6836544 | 0.69 | AR (0.58) | ARPGRNR3C2LMNAMAPT | |
| SCHEMBL7700797 | 0.69 | AR (0.58) | ARPGRNR3C2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238150-B1 | 15,16-METHYLENE-17-HYDROXY-19-NOR-21-CARBOXYLIC ACID y-LACTONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER IP GMBH (DE) | 2012-10-24 | — | — | EP | disclosed |