Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 19/20 | 0.65 |
| ▸ | AR | P10275 | 19/20 | 0.65 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13556634 | 0.91 | PGR (0.78) | PGRARNR3C2 | |
| SCHEMBL12943049 | 0.91 | PGR (0.78) | PGRARNR3C2 | |
| SCHEMBL12998930 | 0.89 | PGR (0.65) | PGRARNR3C2LMNAABCC4 | |
| SCHEMBL14949843 | 0.87 | PGR (0.62) | PGRARNR3C2LMNAABCC4 | |
| SCHEMBL12943047 | 0.81 | AR (0.76) | PGRARNR3C2 | |
| SCHEMBL16572798 | 0.81 | AR (0.76) | PGRARNR3C2 | |
| SCHEMBL16572811 | 0.81 | AR (0.75) | PGRARNR3C2 | |
| SCHEMBL13796418 | 0.81 | AR (0.75) | PGRARNR3C2 | |
| SCHEMBL12942947 | 0.81 | AR (0.75) | PGRARNR3C2 | |
| SCHEMBL13768715 | 0.81 | AR (0.75) | PGRARNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238150-B1 | 15,16-METHYLENE-17-HYDROXY-19-NOR-21-CARBOXYLIC ACID y-LACTONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER IP GMBH (DE) | 2012-10-24 | — | — | EP | disclosed |