Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 17/20 | 0.53 |
| ▸ | PGR | P06401 | 17/20 | 0.53 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12906928 | 1.00 | AR (0.53) | ARPGRNR3C2NR1I2SLC6A4 | |
| SCHEMBL12906958 | 0.89 | AR (0.67) | ARPGRNR3C2LMNA | |
| SCHEMBL12906924 | 0.89 | AR (0.67) | ARPGRNR3C2LMNA | |
| SCHEMBL12906909 | 0.87 | AR (0.51) | ARPGRNR3C2 | |
| SCHEMBL12904855 | 0.85 | AR (0.51) | ARPGRNR3C2NR1I2SLC6A4 | |
| SCHEMBL12942946 | 0.84 | AR (0.45) | ARPGRNR3C2NR1I2SLC6A4 | |
| SCHEMBL12906922 | 0.83 | PGR (0.51) | ARPGRNR3C2NR1I2SLC6A4 | |
| SCHEMBL16404185 | 0.82 | AR (0.78) | ARPGRNR3C2NR1I2SLC6A4 | |
| SCHEMBL12906933 | 0.81 | PGR (0.42) | ARPGRNR3C2NR1I2SLC6A4 | |
| SCHEMBL12906925 | 0.81 | PGR (0.53) | ARPGRNR3C2NR1I2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238150-B1 | 15,16-METHYLENE-17-HYDROXY-19-NOR-21-CARBOXYLIC ACID y-LACTONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER IP GMBH (DE) | 2012-10-24 | — | — | EP | disclosed |