SCHEMBL1355678

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1356713	0.92	MAPT (0.51)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL1355784	0.84	EIF2AK4 (0.59)	LMNAEIF2AK4MAPTGAANPSR1
	SCHEMBL1356097	0.83	MAPT (0.52)	LMNAEIF2AK4MAPTHTTNPSR1
	SCHEMBL1356669	0.83	EIF2AK4 (0.57)	LMNAEIF2AK4MAPTULK1GAA
	SCHEMBL1355806	0.82	EIF2AK4 (0.56)	LMNAEIF2AK4MAPTGAANPSR1
	SCHEMBL1353591	0.82	EIF2AK4 (0.56)	LMNAEIF2AK4MAPTGAANPSR1
	SCHEMBL1355529	0.82	EIF2AK4 (0.53)	EIF2AK4MAPTNPSR1AURKACDK4
	SCHEMBL1355283	0.81	EIF2AK4 (0.52)	LMNAEIF2AK4MAPTNPSR1AURKA
	SCHEMBL1355852	0.81	FGFR4 (0.63)	EIF2AK4AURKACDK4NPC1RAB9A
	SCHEMBL1353652	0.80	CDK4 (0.54)	EIF2AK4MAPTHTTNPSR1AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.