Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12797473 | 1.00 | BCL2L1 (0.36) | BCL2L1MCL1RAB9AMAPTHDAC3 | |
| SCHEMBL12796847 | 0.93 | BCL2L1 (0.38) | BCL2L1MCL1RAB9AMAPTHDAC3 | |
| SCHEMBL12796846 | 0.93 | BCL2L1 (0.38) | BCL2L1MCL1RAB9AMAPTHDAC3 | |
| SCHEMBL12797476 | 0.89 | BCL2L1 (0.42) | BCL2L1MCL1RAB9AMAPTHDAC3 | |
| SCHEMBL23567606 | 0.88 | BCL2L1 (0.43) | BCL2L1MCL1RAB9AMAPTHDAC3 | |
| SCHEMBL12797452 | 0.88 | BCL2L1 (0.43) | BCL2L1MCL1RAB9AMAPTHDAC3 | |
| SCHEMBL19061829 | 0.86 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL13556946 | 0.84 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL12797485 | 0.83 | CYP2A6 (0.36) | BCL2L1MCL1HDAC3HDAC4HDAC1 | |
| SCHEMBL12433613 | 0.82 | CYP2A6 (0.50) | BCL2L1MCL1RAB9AMAPTHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2483367-B1 | ELECTROLUMINESCENT THIOPHENE DERIVATIVES | LOMOX LTD (GB) | 2015-09-16 | — | — | EP | disclosed |
| US-9006435-B2 | Electroluminescent thiophene derivatives | LOMOX LIMITED (GB) | 2015-04-14 | — | — | US | disclosed |
| US-9006435-B2 | Electroluminescent thiophene derivatives | LOMOX LIMITED (GB) | 2015-04-14 | — | — | US | disclosed |
| US-20120271052-A1 | ELECTROLUMINESCENT THIOPHENE DERIVATIVES | LOMOX LIMITED (GB) | 2012-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120271052-A1 | ELECTROLUMINESCENT THIOPHENE DERIVATIVES | AR, NR2E3, NES | BCL2L1 1302/4885MCL1 4238/4885RAB9A 1560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.