Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 13/20 | 0.65 |
| ▸ | PGR | P06401 | 12/20 | 0.65 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.51 |
| ▸ | SHBG | P04278 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12904896 | 1.00 | AR (0.65) | ARPGRNR3C2LMNASLC6A4 | |
| SCHEMBL12904814 | 1.00 | AR (0.65) | ARPGRNR3C2LMNASLC6A4 | |
| SCHEMBL15417491 | 0.89 | PGR (0.52) | ARPGRNR3C2LMNASLC6A4 | |
| SCHEMBL13797342 | 0.88 | AR (0.52) | ARPGRNR3C2LMNASLC6A4 | |
| SCHEMBL12904833 | 0.87 | NR1I2 (0.53) | ARPGRNR3C2LMNASLC6A4 | |
| SCHEMBL12904900 | 0.86 | AR (0.56) | ARPGRNR3C2LMNASLC6A4 | |
| SCHEMBL12904972 | 0.86 | AR (0.56) | ARPGRNR3C2LMNASLC6A4 | |
| SCHEMBL12904827 | 0.86 | AR (0.56) | ARPGRNR3C2LMNASLC6A4 | |
| SCHEMBL12904815 | 0.86 | AR (0.67) | ARPGRNR3C2 | |
| SCHEMBL12904874 | 0.86 | AR (0.67) | ARPGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238148-B1 | 15,16-METHYLENE-17-(1'-PROPENYL)-17,3'-OXIDOESTRA-4-EN-3-ONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER IP GMBH (DE) | 2012-10-24 | — | — | EP | disclosed |