Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.59 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.57 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | GRM5 | P41594 | 4/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9030135 | 0.89 | PTPN7 (0.58) | SLC22A6SLC22A8HTTPTPN7DUSP3 | |
| SCHEMBL16972143 | 0.85 | PTPN7 (0.56) | SLC22A6SLC22A8HTTPTPN7DUSP3 | |
| SCHEMBL18271231 | 0.85 | PTPN7 (0.56) | SLC22A6SLC22A8HTTPTPN7DUSP3 | |
| SCHEMBL1355687 | 0.83 | HTT (0.58) | SLC22A6SLC22A8HTTPTPN7DUSP3 | |
| SCHEMBL239375 | 0.82 | MAPK14 (0.60) | PTPN7DUSP3ALDH1A1HPGDLMNA | |
| SCHEMBL2473674 | 0.82 | MEN1 (0.65) | ALDH1A1KMT2AMEN1CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL9639296 | 0.81 | MEN1 (0.64) | ALDH1A1KMT2AMEN1CYP2D6CYP2C9 | |
| SCHEMBL2546256 | 0.78 | MAPK14 (0.52) | ALDH1A1MAPTKMT2AMEN1MAPK14 | |
| SCHEMBL13175579 | 0.78 | HTR4 (0.46) | KMT2AMEN1GRM5CYP2D6CYP2C9 | |
| SCHEMBL456358 | 0.77 | MAPK14 (0.51) | ALDH1A1KMT2AMEN1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110280940-A1 | Di-Vanilloyl And Tri-Vanilloyl Derivatives For Use In Anti-Cancer Therapy | KISS ROBERT (BE) | 2011-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110280940-A1 | Di-Vanilloyl And Tri-Vanilloyl Derivatives For Use In Anti-Cancer Therapy | PSEN2, PSEN1, VHL | SLC22A6 2419/4885SLC22A8 2037/4885HTT 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.