SCHEMBL13558414

SCHEMBL13558414

Cc1cccc(Nc2ccc3c(c2)Cc2cc(Nc4cccc(C)c4)ccc2-3)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.58
RAB9A P51151 3/20 0.48
NPC1 O15118 1/20 0.48
MAPK14 Q16539 2/20 0.45
HTT P42858 4/20 0.44
MAPT P10636 4/20 0.44
CYP1A2 P05177 3/20 0.44
CYP3A4 P08684 2/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
ADRA2A P08913 1/20 0.44
MAOA P21397 1/20 0.44
SLC6A2 P23975 1/20 0.44
HTR2C P28335 1/20 0.44
SLC6A4 P31645 1/20 0.44
HTR2B P41595 1/20 0.44
NFKB1 P19838 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
LMNA P02545 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13174486 0.83 APP (0.51) NPSR1RAB9ANPC1MAPK14MAPT
SCHEMBL7168804 0.81 HSD17B10 (0.54) NPSR1MAPK14MAPTCYP1A2CYP3A4
SCHEMBL1922070 0.80 NPSR1 (0.86) NPSR1HTTMAPTCYP1A2CYP3A4
SCHEMBL30145137 0.80 NPSR1 (0.86) NPSR1HTTMAPTCYP1A2CYP3A4
SCHEMBL10523964 0.80 NPSR1 (0.86) NPSR1HTTMAPTCYP1A2CYP3A4
SCHEMBL1009206 0.80 NPSR1 (0.86) NPSR1HTTMAPTCYP1A2CYP3A4
SCHEMBL29650380 0.80 NPSR1 (0.86) NPSR1HTTMAPTCYP1A2CYP3A4
SCHEMBL20814558 0.80 NPSR1 (0.41) NPSR1RAB9ANPC1MAPK14MAPT
SCHEMBL10755679 0.79 NPSR1 (0.64) NPSR1HTTMAPTCYP1A2CYP3A4
SCHEMBL9158496 0.78 NPSR1 (0.82) NPSR1HTTMAPTCYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9780308-B2 Composition and light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-10-03 US disclosed
US-9780308-B2 Composition and light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-10-03 US disclosed
US-20120306358-A1 COMPOSITION AND LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-12-06 US disclosed
US-20120306358-A1 COMPOSITION AND LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-12-06 US disclosed
EP-2518111-A1 COMPOSITION AND LUMINESCENT ELEMENT OBTAINED USING SAME Sumitomo Chemical Company, Limited (JP) 2012-10-31 EP disclosed