SCHEMBL20814558

SCHEMBL20814558

Cc1ccc(Nc2ccc3c(c2)Cc2cc(Nc4ccc(C)c(Cc5cccc(Nc6ccc7c(c6)Cc6cc(Nc8cccc(C)c8)ccc6-7)c5)c4)ccc2-3)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.41
RAPGEF4 Q8WZA2 1/20 0.35
HPGD P15428 1/20 0.35
NPC1 O15118 3/20 0.34
RAB9A P51151 3/20 0.34
MAPK14 Q16539 2/20 0.34
KMT2A Q03164 3/20 0.34
MAPT P10636 2/20 0.34
MEN1 O00255 2/20 0.34
SAE1 Q9UBE0 1/20 0.34
UBA2 Q9UBT2 1/20 0.34
RECQL P46063 1/20 0.34
KIF11 P52732 1/20 0.34
APP P05067 1/20 0.33
PDGFRB P09619 2/20 0.33
ALDH1A1 P00352 1/20 0.33
KIT P10721 1/20 0.33
FLT1 P17948 1/20 0.33
KDR P35968 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13558414 0.80 NPSR1 (0.58) NPSR1HPGDNPC1RAB9AMAPK14
SCHEMBL13174486 0.75 APP (0.51) NPSR1RAPGEF4HPGDNPC1RAB9A
SCHEMBL3040701 0.71 NPSR1 (0.79) NPSR1RAPGEF4HPGDKMT2AMAPT
SCHEMBL11502241 0.71 NPSR1 (0.79) NPSR1RAPGEF4HPGDKMT2AMAPT
SCHEMBL8094710 0.69 TAAR1 (0.47) HPGDALDH1A1
SCHEMBL7168804 0.68 HSD17B10 (0.54) NPSR1HPGDMAPK14KMT2AMAPT
SCHEMBL30145137 0.67 NPSR1 (0.86) NPSR1HPGDKMT2AMAPTMEN1
SCHEMBL10523964 0.67 NPSR1 (0.86) NPSR1HPGDKMT2AMAPTMEN1
SCHEMBL1922070 0.67 NPSR1 (0.86) NPSR1HPGDKMT2AMAPTMEN1
SCHEMBL10755679 0.66 NPSR1 (0.64) NPSR1RAPGEF4HPGDKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2518111-B1 COMPOSITION AND LUMINESCENT ELEMENT OBTAINED USING SAME SUMITOMO CHEMICAL CO (JP) 2019-03-13 EP disclosed